7-Chloro-3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidine | 673475-50-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 7-Chloro-3-cyclopentyl-5-phenylpyrazolo[1,5-a]pyrimidine
• CAS: 673475-50-8
• 化学式: C₁₇H₁₆ClN₃
• 分子量: 297.787
• InChiKey: ZVHMEOSMKUGBRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS
  申请人：Schering Corporation

  公开号：EP1534710B1

  公开（公告）日：2007-10-24
• NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS
  申请人：Guzi J. Timothy

  公开号：US20070275983A1

  公开（公告）日：2007-11-29

  In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
• US7309705B2
  申请人：——

  公开号：US7309705B2

  公开（公告）日：2007-12-18
• US7511049B2
  申请人：——

  公开号：US7511049B2

  公开（公告）日：2009-03-31