phenylboronic acid pinacol ester | 856839-54-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenylboronic acid pinacol ester
• 英文别名: (3-Hydroxy-2,3-dimethylbutan-2-yl)oxy-phenylborinic acid
• CAS: 856839-54-8
• 化学式: C₁₂H₁₉BO₃
• 分子量: 222.092
• InChiKey: FFDJYRFFEQSMAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.94
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  phenylboronic acid pinacol ester 在 盐酸 作用下， 生成 9-(biphenyl-4-yl)nonanoic acid
  参考文献：
  名称：

  NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE

  摘要：

  The present invention aims to provide a compound acting as a specific agonist for LPA4 receptors, and a pharmaceutical composition containing the compound. The present invention relates to a novel lysophosphatidic acid derivative having an agonistic action on LPA4 receptors and useful for the prophylaxis and/or treatment of diseases associated with angiogenesis abnormalities involving LPA4 receptors, diseases associated with vascular disorders, or the symptoms associated therewith, and a pharmaceutical composition containing the derivative.

  公开号：

  US20230146210A1

文献信息

• Inhibitors of viral replication, their process of preparation and their therapeutical uses
  申请人：LABORATOIRE BIODIM

  公开号：EP2716639A1

  公开（公告）日：2014-04-09

  The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.

  本发明涉及化合物，其用于治疗或预防病毒性疾病，包括HIV。
• IMIDAZOLE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF INFECTIOUS DISEASES
  申请人：Eberhard Karls Universität Tübingen Medizinische Fakultät

  公开号：EP4197596A1

  公开（公告）日：2023-06-21

  The invention relates to a novel compound for the treatment and prophylaxis of a disease, especially a bacterial infectious disease, for reducing pathogen virulence and promoting host-induced clearance of infection and/or sensitizing bacteria to antibiotic treatment, a method for preparing said compound, a pharmaceutical composition comprising said compound, and to a method for the treatment and/or prophylaxis of a disease, preferably a bacterial infectious disease.

  本发明涉及一种用于治疗和预防疾病的新颖化合物，特别是用于治疗细菌感染性疾病，通过降低病原体的毒力、促进宿主清除感染、以及/或使细菌对抗生素治疗敏感的化合物。本发明还涉及制备所述化合物的方法、包含所述化合物的药物组合物，以及用于治疗和/或预防疾病，优选细菌感染性疾病的方法。
• Synthesis and characterization of air-stable iron-based catalysts for Suzuki-Miyaura cross-coupling reactions of alkyl halides and aryl boronic esters
  申请人：The Trustees of Boston College

  公开号：US12076715B1

  公开（公告）日：2024-09-03

  This disclosure relates to novel catalysts for Suzuki-Miyaura cross-coupling reactions, the use thereof, and the methods of making the same.