| 161959-47-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 161959-47-3
• 化学式: C₁₅H₁₄F₄N₇PS
• 分子量: 431.356
• InChiKey: NVHDMMZXPHZFKP-UCNRHKCTSA-N

反应信息

• 作为反应物：
  描述：

  二(氰基苯)二氯化钯 、 以 二氯甲烷 为溶剂， 以85%的产率得到[PdCl2(PhP(S)(NMeNH2)(NMeN=CHC6F4N3-4))]
  参考文献：
  名称：

  Phosphorus hydrazides as building blocks for potential photoaffinity labels. Synthesis and co-ordination chemistry of perfluoroaryl azide conjugates of phenylphosphonothioic dihydrazide

  摘要：

  The phosphorus hydrazide PhP(S)(NMeNH2)2 1 reacted with the azido functionalized aldehyde 4-N3C6F4CHO to give a mixture of Schiff-base adducts with one or two perfluoroaryl azido substituents on 1. However, the reaction with R'CHO (R = 4-O2NC6H4, 3-O2NC6H4 or 2,4-Me2C6H3) resulted in a considerable selectivity of incorporating one aromatic substituent in the terminal hydrazide unit of 1 via Schiff-base coupling to produce PhP(S) (NMeNH2) (NMeN=CHR') (R' = 4-O2NC6H4 3, 3-O2NC6H4 4 or 2,4-Me2C6H3 5). These mono-Schiff-base adducts 3-5 undergo further Schiff-base coupling with azidotetrafluorobenzaldehyde to produce the azido-functionalized phosphorus hydrazides PhP(S)-(NMeN=CHC6F4N3) (NMeN=CHR') (R' = 4-O2NC6H4 7, 3-O2NC6H4 8 or 2,4-Me2C6H3 9). The ligating properties of the representative phosphorus hydrazides 2 and 9 with palladium(II) were investigated. The crystal structure of the complex [PdCl2{PhP(S)(NMeNH2) (NMeN=CHC6F4N3-4)}] reveals that the palladium(II) is bound in a chelating cis arrangement to the phosphorus chalcogenide and the hydrazine nitrogen via a five-membered metallacyclic framework: monoclinic, space group P2(1)/n, a = 7.826(10), b = 18.051(20), c = 18.330(3) angstrom, beta = 98.196(7)-degrees, Z = 4, R = 0.038 and R' = 0.053.

  DOI：

  10.1039/dt9950000565