| 537678-82-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 537678-82-3
• 化学式: C₂₂H₁₉Cl₄N₂OPt
• 分子量: 664.298
• InChiKey: MCSIMUBOYZAKSE-SIOCZRQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  、 苯 以 水 、 苯 为溶剂， 生成
  参考文献：
  名称：

  Comparative Gas-Phase and Solution-Phase Investigations of the Mechanism of C−H Activation by [(N−N)Pt(CH₃)(L)]⁺

  摘要：

  Contrary to previous claims in the literature, there is no solvent assistence by 2,2,2-trifluoroethanol (TFE) in C-H activation reactions by cationic Pt(II) complexes. Both electrospray ionization tandem mass spectrometric studies of isolated gas-phase intermediates and solution-phase kinetic spectroscopy indicate that TFE serves only as an inert diluent. TFE was found, in the gas-phase experiment to provide no acceleration of the loss of methane or benzene from preselected [(N-N)Pt(CH3)(C6H6)](+) or [(N-N)Pt(CH4)(C6H5)](+) ions. In solution, the overall C-H activation reaction of benzene by [(N-N)Pt(CH3)(H2O)]+BF4- was found to be zero-order in TFE. While it is on one hand disappointing that the claimed facilitation of C-H activation by solvent assistance by TFE at the rate-determining transition state is not supported by the present experimental data, it is on the other hand encouraging that extremely rapid C-H activation (on the time scale of seconds at room temperature) in solution may be achieved in ordinary solvents as long as the solvent is not strongly coordinating.

  DOI：

  10.1021/om0209982