3-benzamido-3-phenylprop-2-enoic acid | 30184-17-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-benzamido-3-phenylprop-2-enoic acid
• CAS: 30184-17-9
• 化学式: C₁₆H₁₃NO₃
• 分子量: 267.284
• InChiKey: JDTUCXUSAVKAJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.54
• 重原子数：
  20.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  66.4
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  ethyl 3-benzamido-3-phenylacrylate 在 氢氧化钾 作用下， 以 异丙醇 为溶剂， 生成 3-benzamido-3-phenylprop-2-enoic acid
  参考文献：
  名称：

  抗炎β-芳基丙烯酸。

  摘要：

  制备了一系列34种β-芳基酰胺基丙烯酸，并检查了其抗炎活性。这些化合物是乙烯基氨基甲酸，在大鼠胸腔积液模型中显示出与苯基丁a相当的几种活性。最高活性与带有卤素和氰基取代基的结构有关。酰胺不活跃。

  DOI：

  10.1021/jm00239a015

文献信息

• Metal complexes useful in metathesis and other reactions
  申请人：Walter Francis

  公开号：US20050043541A1

  公开（公告）日：2005-02-24

  This invention provides metal complexes being useful as catalyst components in metathesis reactions and in reactions involving the transfer of an atom or group to an ethylenically or acetylenically unsaturated compound or another reactive substrate and, with respect to a sub-class thereof, for the polymerisation of α-olefins and optionally conjugated dienes, with high activity at moderate tempera-tures. It also provides methods for obtaining polymers with very narrow molecular weight distribution by means of a living reaction. It also provides methods for making said metal complexes and novel intermediates involved in such methods. It further provides derivatives of said metal complexes which are suitable for covalent bonding to a carrier, the product of such covalent bonding being useful as a supported catalyst for heterogeneous catalytic reactions. It also provides a direct one-step synthesis of pyrrole, furan and thiophene compounds from diallyl compounds.

  本发明提供了金属配合物，可用作交换反应中的催化剂组分，以及涉及将原子或基团转移至乙烯基或乙炔基不饱和化合物或其他反应底物的反应中，并且针对其亚类别，用于α-烯烃和可选的共轭二烯的聚合，具有在中等温度下高活性。它还提供了通过活性反应获得非常窄的分子量分布的聚合物的方法。它还提供了制备该金属配合物和涉及这种方法的新型中间体的方法。它还提供了该金属配合物的衍生物，适用于与载体进行共价键合，该共价键合的产物可用作异相催化反应的支持催化剂。它还提供了从双烯基化合物直接合成吡咯、呋喃和噻吩化合物的一步法。
• Metal complexes for use in olefin methathesis and atom or group transfer reactions
  申请人：UNIVERSITEIT GENT

  公开号：EP1577282A2

  公开（公告）日：2005-09-21

  Improved catalysts useful in a number of organic synthesis reactions such as olefin metathesis and atom or group transfer reactions are made by bringing into contact a multi-coordinated metal complex comprising a multidentate Schiff base ligand, and one or more other ligands, with an acid under conditions such that said acid is able to at least partly cleave a bond between the metal and the multidentate Schiff base ligand of said metal complex, optionally through intermediate protonation of said Schiff base ligand.

  在烯烃复分解反应和原子或基团转移反应等一系列有机合成反应中使用的改良催化剂，是通过将包含多叉席夫碱配体和一个或多个其他配体的多配位金属络合物与酸接触而制成的，接触条件是所述酸能够至少部分裂解金属与所述金属络合物的多叉席夫碱配体之间的键，还可选择通过所述席夫碱配体的中间质子化。
• Phosphine derivative and polymer thereof and transition metal complex comprising the same
  申请人：Takasago International Corporation

  公开号：EP1041077B1

  公开（公告）日：2003-11-05
• ASYMMETRIC SYNTHESIS CATALYZED BY TRANSITION METAL COMPLEXES WITH CYCLIC CHIRAL PHOSPHINE LIGANDS
  申请人：THE PENN STATE RESEARCH FOUNDATION

  公开号：EP0918781B1

  公开（公告）日：2004-02-18
• Process for producing optically active alcohols
  申请人：Takasago Perfumery Co., Ltd.

  公开号：EP0258967B2

  公开（公告）日：1996-08-21