1-benzyl-3-methyl-3-cyclohexenol | 946848-13-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-benzyl-3-methyl-3-cyclohexenol
• CAS: 946848-13-1
• 化学式: C₁₄H₁₈O
• 分子量: 202.296
• InChiKey: JXDZTMDKXCKNDK-CQSZACIVSA-N

反应信息

• 作为反应物：
  描述：

  双(乙腈)氯化钯(II) 、 1-benzyl-3-methyl-3-cyclohexenol 以 1,4-二氧六环 为溶剂， 以74%的产率得到Pd[η3-HOC(CH2Ph)CH2C(Me)=CHCH2CH2]Cl2
  参考文献：
  名称：

  Palladium-Mediated Cyclization of 6-Methyl-1-phenyl-6-hepten-2-one to Form 3-Methyldiphenylmethane:  Carbonyl Activation by a Neutral Palladium(II) Complex

  摘要：

  Reaction of 6-methyl-1-phenyl-6-hepten-2-one (4) with a stoichiometric mixture of PdCl2(CH3CN)(2) (2) and Me3SiCl in dioxane at 70 degrees C formed 3-methyldiphenylmethane (6) in 78% isolated yield. A number of experiments supported a mechanism for the conversion of 4 to 6 initiated by palladium-mediated carbonyl-ene reaction to form the isolable palladium alkene-alcohol complex[GRAPHICS](7) followed by Me3SiCl-mediated dehydration to form the unobserved palladium diene complex[GRAPHICS](II) and palladium-mediated oxidation of II to form 6.

  DOI：

  10.1021/om700379g