1-(2-Phenylethenyl)cyclopropan-1-amine | 604799-99-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2-Phenylethenyl)cyclopropan-1-amine
• CAS: 604799-99-7
• 化学式: C₁₁H₁₃N
• 分子量: 159.23
• InChiKey: SRQFAPCKOFPXIZ-UHFFFAOYSA-N

物化性质

• 沸点：
  253.7±19.0 °C(Predicted)
• 密度：
  1.159±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• LSD1 INHIBITORS AND USES THEREOF
  申请人：Constellation Pharmaceuticals, Inc.

  公开号：US20180290976A1

  公开（公告）日：2018-10-11

  Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with LSD1. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with LSD1.