Ethyl-(2-methoxy-pyridin-4-YL)-amine | 1220039-68-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Ethyl-(2-methoxy-pyridin-4-YL)-amine
• 英文别名: N-ethyl-2-methoxypyridin-4-amine
• CAS: 1220039-68-8
• 化学式: C₈H₁₂N₂O
• 分子量: 152.19
• InChiKey: JZZSXVMMDOUJLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  34.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] BIPHENYL DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF<br/>[FR] INHIBITEUR DE DÉRIVÉ BIPHÉNYLE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION<br/>[ZH] 联苯类衍生物抑制剂、其制备方法和应用
  申请人：SHANGHAI HANSOH BIOMEDICAL CO LTD

  公开号：WO2021136354A1

  公开（公告）日：2021-07-08

  一种通式(Ib)所示的联苯类衍生物抑制剂及其在制备治疗癌症、感染性疾病、自身免疫性疾病药物中的用途。
• SUBSTITUTED AMINE DERIVATIVES AND METHODS OF USE IN THE TREATMENT OF ANGIOGENESIS RELATED DISORDERS
  申请人：Amgen Inc.

  公开号：EP1562933A2

  公开（公告）日：2005-08-17
• [EN] SUBSTITUTED AMINE DERIVATIVES AND METHODS OF USE IN THE TREATMENT OF ANGIOGENESIS RELATES DISORDERS<br/>[FR] DERIVES D'AMINES SUBSTITUEES ET PROCEDES D'UTILISATION
  申请人：AMGEN INC

  公开号：WO2004007481A2

  公开（公告）日：2004-01-22

  Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.