S-2-Pentyl-thiuronium | 44815-49-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 异硫脲类
• 英文名称: S-2-Pentyl-thiuronium
• 英文别名: S-(1-methyl-butyl)-isothiourea；S-(1-Methyl-butyl)-isothioharnstoff；Pentan-2-yl carbamimidothioate
• CAS: 44815-49-8
• 化学式: C₆H₁₄N₂S
• 分子量: 146.257
• InChiKey: SYSVSWKUBXXGAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  75.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] AMINOHETEROARYL COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS AMINOHÉTÉROARYLES ET LEURS UTILISATIONS
  申请人：[en]BEIJING ERAI THERAPEUTICS CO., LTD.

  公开号：WO2022147694A1

  公开（公告）日：2022-07-14

  Provided herein are novel compounds (e.g., Formula I, II, III, or IV), pharmaceutical compositions, and methods of using the same. The compounds herein can typically induce UCP-1 expression and/or browning of white adipose tissues. The compounds herein can also be used for treating a variety of diseases or disorders, such as a metabolic disease or disorder such as obesity and/or diabetes (e.g., Type 2 diabetes) and/or a liver disease or disorder such as NASH and/or non-alcoholic fatty liver disease.