1,1'-Terephthaloyl-bis-(4-allyl-3-thiosemicarbazid) | 21084-65-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1'-Terephthaloyl-bis-(4-allyl-3-thiosemicarbazid)
• CAS: 21084-65-1
• 化学式: C₁₆H₂₀N₆O₂S₂
• 分子量: 392.506
• InChiKey: XZAVRYCBGHDMHI-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  1,1'-Terephthaloyl-bis-(4-allyl-3-thiosemicarbazid) 在 potassium hydroxide 作用下， 以 水 为溶剂， 生成 2,2'-{benzene-1,4-diylbis[(4-allyl-4H-1,2,4-triazole-3,5-diyl)sulfanediyl]}diacetic acid
  参考文献：
  名称：

  New Bis-4H-1,2,4-triazoles and Their In Vitro Study as DNA Methylation Inhibitors

  摘要：

  Bis-1,2,4-triazoles with aryl and alkyl linkers were synthesized. In order to increase their hydrophilicity and potential biological activity, pharmacophore electron-deficient groups (carboxylic, carboxamide, nitrile) were introduced into the molecule. Functionalized compounds revealed a new type of biological activity such as inhibition of the level of methylation of tumor DNA.

  DOI：

  10.1134/s1070363220050047