| 846606-18-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 846606-18-6
• 化学式: C₃₀H₂₆F₆O₈S₂
• 分子量: 692.654
• InChiKey: IMSHJFCOACPDDA-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 palladium diacetate 、 1,4-双(二苯基膦)丁烷 三氯硅烷 、 N,N-二异丙基乙胺 作用下， 以 二甲基亚砜 、 甲苯 为溶剂， 反应 36.0h， 生成 (26-Diphenylphosphanyl-10,19-dioxapentacyclo[18.6.2.26,9.02,7.023,27]triaconta-1(26),2,4,6,8,20(28),21,23(27),24,29-decaen-3-yl)-diphenylphosphane
  参考文献：
  名称：

  Preparation of chiral 7,7′-disubstituted BINAPs for Rh-catalyzed 1,4-addition of arylboronic acids

  摘要：

  A series of new 7,7'-disubstituted BINAPs were readily prepared starting with an asymmetric catalytic oxidative coupling. They were applied as ligands to rhodium catalyzed 1,4-addition of arylboronic acids to enone,. resulting in enantioselectvities of up to 99% ee. The enantioselectivity was found to be dependent oil the size of achiral substituents. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.11.096
• 作为产物：
  描述：

  三氟甲磺酸酐 、 10,19-dioxapentacyclo[18.6.2.26,9.02,7.023,27]triaconta-1(26),2,4,6,8,20(28),21,23(27),24,29-decaene-3,26-diol 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 以93%的产率得到
  参考文献：
  名称：

  A class of readily available optically pure 7,7′-disubstituted BINAPs for asymmetric catalysis

  摘要：

  A class of optically pure 7,7'-disubstituted BINAPs have been prepared starting with a catalytic asymmetric oxidative Coupling reaction. A general, concise, and straightforward synthetic procedure has been established, and is suitable for all optically pure 7,7'-disubstituted BINAPs 1a-h, regardless of the substituents' structure in the 7,7'-positions. The catalytic potential of this class of ligands has been investigated in the highly enantioselective Rh-catalyzed 1,4-addition of aryl boronic acids to enones (up to 99.8% ee), and Ru-catalyzed asymmetric hydrogenation of simple aromatic ketones (up to S/C=100,000, up to 98% ee) and beta-ketoesters (up to S/C= 10,000, up to 99.8% ee), respectively. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.03.066