4-乙基噻吩并[2,3-b]吡啶 | 28988-17-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩并吡啶类
• 中文名称: 4-乙基噻吩并[2,3-b]吡啶
• 英文名称: 4-ethylthieno<2,3-b>pyridine
• 英文别名: 4-Ethylthieno[2,3-b]pyridine
• CAS: 28988-17-2
• 化学式: C₉H₉NS
• 分子量: 163.243
• InChiKey: GLMJJOHXUWISKS-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1-戊烯-3-酮 、 bis(2-thienylammonium)hexachlorostannate(IV) 以 乙醇 为溶剂， 以45%的产率得到4-乙基噻吩并[2,3-b]吡啶
  参考文献：
  名称：

  Klemm, L. H.; Shabtai, J.; Michaud, Joan, Journal of Heterocyclic Chemistry, 1981, vol. 18, p. 1383 - 1387

  摘要：

  DOI：

文献信息

• Fused heterocyclic derivatives and methods of use
  申请人：Albrecht Brian K.

  公开号：US20090124612A1

  公开（公告）日：2009-05-14

  Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

  所选化合物对于预防和治疗疾病，如HGF介导的疾病具有有效性。本发明包括新颖的化合物、类似物、前药和其药学上可接受的盐、药物组合物和预防和治疗涉及癌症等疾病和其他疾病或病况的方法。该发明还涉及制备这样的化合物的过程，以及在这样的过程中有用的中间体。
• HETEROARYLS AND USES THEREOF
  申请人：Freeze Brian S.

  公开号：US20120172345A1

  公开（公告）日：2012-07-05

  This invention provides compounds of formula IA-i-a or IB-i-a and subsets thereof: wherein Z, HY, R 1 , R 2 , R 3 , G 1 , W, n, and A and subsets thereof are as described in the specification. The compounds are inhibitors of PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

  本发明提供了式IA-i-a或IB-i-a及其子集的化合物:其中Z、HY、R1、R2、R3、G1、W、n和A及其子集如说明书所述。这些化合物是PI3K的抑制剂，因此可用于治疗增殖、炎症或心血管疾病。
• FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE
  申请人：Albrecht Brian K.

  公开号：US20120107275A1

  公开（公告）日：2012-05-03

  Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

  所选化合物可用于预防和治疗疾病，如HGF介导的疾病。本发明涵盖了新颖的化合物、类似物、前药和其药学上可接受的盐、药物组合物以及预防和治疗涉及癌症等疾病和其他不适或病况的方法。本发明还涉及制备这种化合物的方法，以及在这些过程中有用的中间体。
• Pyridazinone herbicides
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：US10750743B2

  公开（公告）日：2020-08-25

  Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, agricultural compositions containing them and their use as herbicides wherein R1, R2, G and W are as defined in the disclosure, and A is selected from and X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, Y1, Y2, and Y4 are as defined in the disclosure.

  公开了式 1 的化合物（包括其所有立体异构体、N-氧化物和盐）、含有它们的农用组合物以及它们作为除草剂的用途 其中 R1、R2、G 和 W 如公开内容中所定义，以及 A 选自 和 X1、X2、X3、X4、X5、X6、X7、X8、X9、X10、Y1、Y2 和 Y4 的定义如本公开所述。
• FAP INHIBITOR
  申请人：UNIVERSITÄT HEIDELBERG

  公开号：US20210038749A1

  公开（公告）日：2021-02-11

  The present invention relates to a compound of formula (I), a pharmaceutical composition comprising or consisting of said compound, a kit comprising or consisting of said compound or pharmaceutical composition and use of the compound or pharmaceutical composition in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP).