N-(4-nitrophenyl)-1,5,3-dithiazocan-3-amine | 1443367-36-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-nitrophenyl)-1,5,3-dithiazocan-3-amine
• 英文别名: N-(4-nitrophenyl)-1,5,3-dithiazocan-3-ylamine
• CAS: 1443367-36-9
• 化学式: C₁₁H₁₅N₃O₂S₂
• 分子量: 285.391
• InChiKey: IYXAPQVTIRXEBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  N¹,N¹,N⁷,N⁷-tetramethyl-2,6-dithiaheptane-1,7-diamine 、 4-硝基苯肼 在 copper dichloride 作用下， 以 氯仿 为溶剂， 反应 1.0h， 以83%的产率得到N-(4-nitrophenyl)-1,5,3-dithiazocan-3-amine
  参考文献：
  名称：

  Hydrazines in the synthesis of N-substituted 1,5,3-dithiazocan-3-amines catalyzed by Ti and Cu compounds

  摘要：

  Efficient preparation method was developed for N-aryl(benzyl, alkyl)-1,5,3-dithiazocan-3-amines consisting in the transamination of 3-tert-butyl-1,5,3-dithiazocane with aryl(benzyl)hydrazines, and also in the reaction of N (1),N (1),N (7),N (7)-tetramethyl-2,6-dithiaheptane-1,7-diamine with aryl(benzyl, alkyl)hydrazines in the presence of catalytic amounts of Ti and Cu compounds.

  DOI：

  10.1134/s1070428013050023

文献信息

• Hydrazines in the synthesis of 1,5,3-dithiazepane and 1,5,3-dithiazocane derivatives in the presence of catalysts under the action of d- and f-elements
  作者：N. N. Makhmudiyarova、R. Sh. Rakhimov、A. G. Ibragimov、U. M. Dzhemilev

  DOI：10.1134/s1070428014020080

  日期：2014.2

  A method of synthesis was developed for 1,5,3-dithiazepan(dithiazocan)-3-ylamines and 3,3'-bi-1,5,3-dithiazepane(dithiazocane) by hydrazines cyclocondensation with formaldehyde and alpha,omega-alkanedithiols (1,2-ethanedithiol, 1,3-propanedithiol) involving catalysts based on d- and f-elements.