(3,5-Diphenylphenyl)-diphenylphosphane | 1072945-42-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3,5-Diphenylphenyl)-diphenylphosphane
• CAS: 1072945-42-6
• 化学式: C₃₀H₂₃P
• 分子量: 414.486
• InChiKey: GTKBYAHIAMINBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  5-diphenylphosphino-1,3-dibromobenzene 、 苯硼酸 在 potassium phosphate 、 水 作用下， 以 甲苯 为溶剂， 反应 5.0h， 以70%的产率得到(3,5-Diphenylphenyl)-diphenylphosphane
  参考文献：
  名称：

  Synthesis and applications of a new palladacycle as a high active catalyst in the Suzuki couplings

  摘要：

  The reaction of biphenyl-based phosphine P(o-C6H4Me)Ph-2 (1) with Pd(OAc)(2) in toluene affords the air and water stable palladacycle (2) as a binuclear compound which has been characterized by multinuclear NMR spectroscopy and elemental analysis as a mixture of cis and trans isomers with relative intensity of 1:3, respectively. This palladacycle is a highly efficient catalyst precursor for the coupling of aryl boronic acids and aryl halides. Both activated and deactivated aryl bromides and chlorides are efficiently coupled in the presence of 2 to furnish the corresponding cross-coupled products in excellent yields, and a wide variety of functional groups are tolerated in aryl halides. This methodology has also been extended for the coupling of bromoarylphosphines and bromoarylphosphine oxides with aryl boronic acids for the generation of hindered corresponding products. (C) 2008 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2008.07.003