6-Cyclohexyl-2-(hydroxymethyl)-3-methylphenol | 408500-49-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-Cyclohexyl-2-(hydroxymethyl)-3-methylphenol
• CAS: 408500-49-2
• 化学式: C₁₄H₂₀O₂
• 分子量: 220.312
• InChiKey: CHJOGIQPKYOXGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Triptolide Analogs for the Treatment of Autoimmune and Inflammatory Disorders
  申请人：Wang Susheng

  公开号：US20090234000A1

  公开（公告）日：2009-09-17

  The present invention provides synthetic methods and compositions for treatment of autoimmune and anti-inflammatory disorders comprising administering an effective amount of a derivative of triptolide alone or in combination or alternation with other anti-autoimmune or anti-inflammatory compounds.
• Branched Diepoxide Compounds for the Treatment of Inflammatory Disorders
  申请人：Liotta Dennis C.

  公开号：US20100324133A1

  公开（公告）日：2010-12-23

  The present invention provides certain diepoxide carbocyclic compounds wherein at least one carbocyclic ring carbon includes two non-epoxide substituents, and pharmaceutical compositions containing the same, for the treatment or prophylaxis of inflammatory, autoimmune and hyper- or abnormally proliferative diseases and disorders.
• US7557139B2
  申请人：——

  公开号：US7557139B2

  公开（公告）日：2009-07-07
• US8193249B2
  申请人：——

  公开号：US8193249B2

  公开（公告）日：2012-06-05
• [EN] BRANCHED DIEPOXIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS<br/>[FR] COMPOSÉS DIÉPOXYDES RAMIFIÉS POUR LE TRAITEMENT DE TROUBLES INFLAMMATOIRES
  申请人：UNIV EMORY

  公开号：WO2009089285A2

  公开（公告）日：2009-07-16

  The present invention provides certain diepoxide carbocyclic compounds wherein at least one carbocyclic ring carbon includes two non-epoxide substituents, and pharmaceutical compositions containing the same, for the treatment or prophylaxis of inflammatory, autoimmune and hyper- or abnormally proliferative diseases and disorders.