1,3-bis[di(2,6-dimethoxy-phenyl)phosphino]propane | 116163-93-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-bis[di(2,6-dimethoxy-phenyl)phosphino]propane
• 英文别名: 3-Bis(2,6-dimethoxyphenyl)phosphanylpropyl-bis(2,6-dimethoxyphenyl)phosphane
• CAS: 116163-93-0
• 化学式: C₃₅H₄₂O₈P₂
• 分子量: 652.661
• InChiKey: WUXOLZRWJZLXBJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  45
• 可旋转键数：
  16
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  73.8
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,3-bis[di(2,6-dimethoxy-phenyl)phosphino]propane 在 氨 、 sodium 作用下， 反应 2.0h， 生成 1,3-Propanediylbis((2,6-dimethoxyphenyl)phosphine)
  参考文献：
  名称：

  碳磷键与碱金属的还原裂解。三，芳基烷基膦的反应

  摘要：

  苯烷基膦Ph 2 PR，PhPR 2（R = Bu，iPr）与Na / NH 3的还原裂解是非选择性的：苯基和烷基都可以裂解，并且可能发生桦木还原。Ph 2 tBuP的反应产生了高产率的二苯基磷化物。伯烷基的ω位置的极性基团（CO 2 Na，SO 3，Na）可能导致选择性增加；桦木还原得到抑制，并获得官能化的仲磷化物。

  DOI：

  10.1002/recl.19921110402

文献信息

• Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides
  申请人：Zierke Thomas

  公开号：US20100174094A1

  公开（公告）日：2010-07-08

  The present invention relates to a process for preparing N-substituted (3-dihalomethylpyrazol-4-yl)carboxamides of the formula (I) in which R 1 is optionally substituted phenyl or C 3 -C 7 -cycloalkyl, R 1a is hydrogen or fluorine, or R 1a together with R 1 is optionally substituted C 3 -C 5 -alkanediyl or C 5 -C 7 -cycloalkanediyl, R 2 is C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl or C 1 -C 4 -alkoxy-C 1 -C 2 -alkyl, X is F or Cl and n is 0, 1, 2 or 3; which comprises A) providing a compound of the formula (II) in which X is F or Cl, Y is Cl or Br and R 2 has one of the meanings given above and B) reacting a compound of the formula (II) with carbon monoxide and a compound of the formula (III) in which R 1 , R 1a and n have one of the meanings given above; in the presence of a palladium catalyst; to intermediates used for the preparation according to the process according to the invention, and also to processes for their preparation.

  本发明涉及一种制备式(I)的N-取代(3-二卤甲基吡唑-4-基)羧酰胺的方法 其中R1是可选的取代苯基或C3-C7环烷基，R1a是氢或氟，或者R1a与R1一起是可选的取代C3-C5-烷二基或C5-C7-环烷二基，R2是C1-C6-烷基，C2-C6-烯基，C2-C6-炔基或C1-C4-烷氧基-C1-C2-烷基，X是F或Cl，n为0、1、2或3；包括 A)提供式(II)的化合物 其中X是F或Cl，Y是Cl或Br，R2具有上述给定的含义之一 B)将式(II)的化合物与一氧化碳和式(III)的化合物反应 其中R1、R1a和n具有上述给定的含义之一；在钯催化剂的存在下； 用于根据本发明的方法制备的中间体，以及用于它们的制备的方法。
• Catalyst compositions, olefin/co copolymerization process and bisphosphine compounds
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0257663A2

  公开（公告）日：1988-03-02

  Novel catalyst composition, characterized in that they are based upon a) a palladium compound, b) an anion of an acid with a pKa of less than 2, with the proviso that the acid is not a hydrohalogenic acid, c) a bisphosphine of the general formula R1R2P-R-PR3R4, wherein R1-R4 are similar or dissimilar hydrocarbyl groups which may or may not be substituted with polar groups, with the proviso that at least one of the groups R1-R4 represents a polarly substituted aryl group containing at least one polar substituent on a position ortho to phosphorus, and wherein R represents a bivalent organic bridging group containing at least two carbon atoms in the bridge, and d) optionally, a quinone.

  新型催化剂组合物，其特征在于它们基于 a) 钯化合物；b) pKa 小于 2 的酸的阴离子，但该酸不是氢卤酸；c) 通式为 R1R2P-R-PR3R4 的双膦，其中 R1-R4 是相似或不相似的烃基，这些烃基可以被极性基团取代，也可以不被极性基团取代，但 R1-R4 中至少有一个基团代表极性取代的芳基，该芳基在磷的正交位置上至少含有一个极性取代基，其中 R 代表在桥中至少含有两个碳原子的二价有机桥基；d) 可选的醌。
• Catalyst compositions and olefin/CO-copolymerization process
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0263564A1

  公开（公告）日：1988-04-13

  Novel catalyst compositions, characterized in that they are based upon a) a palladium compound, b) an anion of an acid with a pKa of at least 2, but less than 6, and c) a bidentate li gand of the general formula R₁R₂M-R-MR₃R₄, wherein M represents phosphorus, arsenic or antimony, R₁, R₂, R₃ and R₄ are hydrocarbyl groups which may or may not be substituted with polar groups, with the proviso that at least one of the groups R₁-R₄ represents a polarly substituted aryl group containing at least one polar substituent in a position ortho to M, and R represents a bivalent organic bridging group containing at least two carbon atoms in the bridge.

  新型催化剂组合物，其特征在于它们基于 a) 钯化合物 b) pKa 至少为 2 但小于 6 的酸阴离子，以及 c) 通式为 R₁R₂M-R-MR₃R₄的双叉锂离子，其中 M 代表磷、砷或锑，R₁、R₂、R₃ 和 R₄ 为可能被或不被极性基团取代的烃基、但其中至少有一个基团 R₁-R₄ 代表被极性取代的芳基，该芳基在 M 的正交位置上含有至少一个极性取代基，而 R 代表在桥中含有至少两个碳原子的二价有机桥基。
• Process for the preparation of polymers of C0 and olefinically unsaturated compounds
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0272728A2

  公开（公告）日：1988-06-29

  1. Novel catalyst compositions, comprising a) a palladium compound, b) an anion of an acid with a pKa of less than 6, c) a bidentate ligand of the general formula R₁R₂M-R-MR₃R₄, wherein M represents phosphorus, arsenic or antimony, R₁,R₂,R₃ and R₄ represent hydrocarbyl groups which may or may not be substituted with polar groups and R is a bivalent organic bridging group having at least two carbon atoms in the bridge, and d) a compound chosen from the group formed by organic nitrites and nitro-compounds.

  1.新型催化剂组合物，包括 a) 钯化合物、 b) pKa 小于 6 的酸阴离子、 c) 通式为 R₁R₂M-R-MR₃R₄的双叉配体，其中 M 代表磷、砷或锑，R₁、R₂、R₃ 和 R₄ 代表可能被或可能不被极性基团取代的烃基，R 是桥中至少有两个碳原子的二价有机桥基，以及 d) 选自有机亚硝酸盐和硝基化合物组的化合物。
• Novel polymers of carbon monoxide and alpha-olefinically unsaturated compounds
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0272727A2

  公开（公告）日：1988-06-29

  Novel polymers of carbon monoxide with one or more -olefinically unsaturated compounds, characterized in that a) they are prepared by the polymerization of one or more compounds (D) comprising a group of the general formula (CH₂=CR₁)- which is bound by a bivalent hydrocarbyl bridging group to monovalent polar group having at least one oxygen, nitrogen, phosphorus and/or halogen atom and, optionally also to one or more compounds (A) of the general formula (CH₂=CR₁)-R₂, in which formulae R₁ and R₂ represent hydrogen atoms and/or monovalent hydrocarbyl groups, b) they have a linear structure, c) they are made up of units of the general formula -CO-(Dʹ)- and optionally also units of the general formula -CO-(Aʹ)-, wherein Aʹ and Dʹ represent monomer units originating in monomers A and D, respectively, used.

  一氧化碳与一种或多种-烯烃不饱和化合物的新型聚合物，其特征在于 a) 它们是由一种或多种化合物（D）聚合制备的，这些化合物（D）包含通式 （CH₂=CR₁）- 的基团，该基团通过二价烃基桥接基团与具有至少一个氧原子、氮原子、磷原子和/或卤原子的一价极性基团以及（可选）一种或多种化合物（A）结合、氮、磷和/或卤原子的一价极性基团，以及通式 (CH₂=CR₁)-R₂ 的一种或多种化合物 (A)，其中式 R₁ 和 R₂ 代表氢原子和/或一价烃基、 b) 它们具有线性结构、 c) 它们由通式-CO-(Dʹ)-的单元和通式-CO-(Aʹ)-的单元组成，其中 Aʹ 和 Dʹ 分别代表来自所用单体 A 和 D 的单体单元。