2-氨基-3-氰基苯甲酸 | 1275585-93-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-氨基-3-氰基苯甲酸
• 英文名称: 2-amino-3-cyano-benzoic acid
• 英文别名: 2-Amino-3-cyan-benzoesaeure；2-Amino-3-cyanobenzoic acid
• CAS: 1275585-93-7
• 化学式: C₈H₆N₂O₂
• 分子量: 162.148
• InChiKey: RWVGEJMJPBHSKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87.1
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  7-Carboxy-isatin-3-oxim 生成 2-氨基-3-氰基苯甲酸
  参考文献：
  名称：

  Bedford; Partridge, Journal of the Chemical Society, 1959, p. 1633

  摘要：

  DOI：

文献信息

• [EN] ANTIBACTERIAL BENZOIC ACID DERIVATIVES<br/>[FR] DERIVES D'ACIDES BENZOIQUES ANTIBACTERIENS
  申请人：UPJOHN CO

  公开号：WO2004018428A1

  公开（公告）日：2004-03-04

  The invention provides antimicrobial agents and methods of using the agents for sterilization, sanitation, antisepsis, disinfection, and treatment of infections in mammals.

  这项发明提供了抗菌剂和使用这些剂进行哺乳动物的消毒、卫生、防腐、消毒和治疗感染的方法。
• [EN] NOVEL ANTHRANILAMIDES USEFUL FOR CONTROLLING INVERTEBRATE PESTS<br/>[FR] NOUVEAUX ANTHRANILAMIDES SERVANT A LUTTER CONTRE DES NUISIBLES INVERTEBRES
  申请人：DU PONT

  公开号：WO2006023783A1

  公开（公告）日：2006-03-02

  Disclosed are compounds of Formula (I), including all geometric and stereoisomers, N oxides, and salts thereof formula (I) wherein Q is selected from the group consisting of formulae (Q-1), (Q-2) and (Q-3); R1 is X-Z-O-R11; X is O, S or NR12; Z is C2-C4 haloalkylene or C2-C4 haloalkenylene; and R2, R3, R4, R5, R6, R7, R11, R12 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  揭示的是Formula (I)的化合物，包括所有的几何和立体异构体、N-氧化物及其盐。其中，Formula (I)中的Q是从(Q-1)、(Q-2)和(Q-3)组成的组中选择的；R1是X-Z-O-R11；X是O、S或NR12；Z是C2-C4卤代烷基或C2-C4卤代烯基；R2、R3、R4、R5、R6、R7、R11、R12和n如披露中定义的那样。还公开了含有Formula I的化合物的组合物，以及用于控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与本发明的化合物或组合物的生物有效量接触。
• [EN] CYANO ANTHRANILAMIDE INSECTICIDES<br/>[FR] INSECTICIDES A BASE DE CYANO-ANTHRANILAMIDE
  申请人：DU PONT

  公开号：WO2004067528A1

  公开（公告）日：2004-08-12

  This invention provides compounds of Formula (I), N -oxides and suitable salts thereof INSERT FORMULA I HERE wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H or C1-C4 alkyl,C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe S(O)Me, S(O)2Me and OMe; R5 is H or Me; R6 is H, F or Cl; and R7 is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula (I), an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula (I), an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.

  这项发明提供了Formula (I)的化合物，N-氧化物及其适当的盐插入Formula I的公式如下：其中R1为Me、Cl、Br或F；R2为F、Cl、Br、C1-C4卤代烷基或C1-C4卤代烷氧基；R3为F、Cl或Br；R4为H或C1-C4烷基、C3-C4烯基、C3-C4炔基、C3-C5环烷基或C4-C6环烷烷基，每个均可选择一个来自卤素、CN、SMe、S(O)Me、S(O)2Me和OMe的取代基；R5为H或Me；R6为H、F或Cl；R7为H、F或Cl。还公开了一种用于控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与Formula (I)的化合物、其N-氧化物或化合物的适当盐（例如，作为本文所述的组合物）的生物有效量接触。这项发明还涉及一种用于控制无脊椎动物害虫的组合物，包括Formula (I)的化合物、其N-氧化物或化合物的适当盐的生物有效量，以及从表面活性剂、固体稀释剂和液体稀释剂中选择的至少一种额外成分。
• METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE
  申请人：Volz Frank

  公开号：US20140148611A1

  公开（公告）日：2014-05-29

  The present invention relates to a process for preparing 2-amino-5-cyano-N,3-dimethylbenzamide of formula (1) by reacting 2-amino-5-cyano-3-methylbenzoic esters or diesters with methylamine.

  本发明涉及一种制备式（1）的2-氨基-5-氰基-N,3-二甲基苯甲酰胺的方法，该方法通过将2-氨基-5-氰基-3-甲基苯甲酸酯或二酯与甲胺反应而得到。
• NOVEL TRICYCLIC PROTEIN KINASE MODULATORS
  申请人：HADDACH Mustapha

  公开号：US20110071136A1

  公开（公告）日：2011-03-24

  The invention provides compounds that inhibit CK2 and/or Pim kinases and compositions containing such compounds. These tricyclic compounds and compositions containing them are useful for treating proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, pathogenic infections, and certain immunological disorders.

  这项发明提供了抑制CK2和/或Pim激酶的化合物以及含有这些化合物的组合物。这些三环化合物和含有它们的组合物对于治疗增殖性疾病如癌症以及其他与激酶相关的疾病条件包括炎症、疼痛、病原体感染和某些免疫性疾病是有用的。