1-methyl-3-fluoromethyl-1H-pyrazole-4-carboxylic acid (2'-chloro-4'-fluorobiphenyl-2-yl)-amide | 907204-91-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-methyl-3-fluoromethyl-1H-pyrazole-4-carboxylic acid (2'-chloro-4'-fluorobiphenyl-2-yl)-amide
• 英文别名: N-[2-(2-chloro-4-fluorophenyl)phenyl]-3-(fluoromethyl)-1-methylpyrazole-4-carboxamide
• CAS: 907204-91-5
• 化学式: C₁₈H₁₄ClF₂N₃O
• 分子量: 361.778
• InChiKey: XAWOJDGFEAAMHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides
  申请人：Dietz Jochen

  公开号：US20090042724A1

  公开（公告）日：2009-02-12

  The present invention relates to fungicidal mixtures comprising, as active components, 1) at least one 2,4-disubstituted N-biphenylpyrazolecarboxamide of the formula I in which X=oxygen or sulfur; R 1 and R 2 =independently of one another cyano, nitro, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, methoxy, difluoromethoxy or trifluoromethoxy; R 3 =halogen, C 1 -C 4 -alkyl or C 1 -C 4 -haloalkyl; R 4 =hydrogen or halogen; and 2 ) at least one active compound II selected from groups A) to F): A) azoles; B) strobilurins; C) carboxamides; D) heterocyclic compounds; E) carbamates; F) other fungicides; in a synergistically effective amount, methods for controlling harmful fungi using mixtures of at least one compound I and at least one active compound II, the use of the compounds I with active compounds II for preparing such mixtures and also compositions and seed comprising these mixtures.

  本发明涉及杀真菌混合物，其包括以下活性成分：1) 至少一种式I的2,4-二取代N-联苯基吡唑甲酰胺，其中X=氧或硫；R1和R2独立地为氰基、硝基、卤素、C1-C6烷基、C1-C6卤代烷基、甲氧基、二氟甲氧基或三氟甲氧基；R3为卤素、C1-C4烷基或C1-C4卤代烷基；R4为氢或卤素；以及2) 至少一种选自A) 至 F) 组的活性化合物II：A) 咪唑类；B) 史托比林；C) 羧酰胺；D) 杂环化合物；E) 氨基甲酸酯；F) 其他杀真菌剂；在协同有效量下，使用至少一种化合物I和至少一种活性化合物II的混合物来控制有害真菌的方法，使用化合物I与活性化合物II制备这种混合物以及包含这些混合物的组合物和种子。
• Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi
  申请人：Gewehr Markus

  公开号：US20080153707A1

  公开（公告）日：2008-06-26

  The present invention relates to pyrazolecarboxanilides I in which the variables are as defined below: n is zero or 2; m is 2 or 3; X 1 is fluorine or chlorine; X 2 is halogen; Y is CN, NO 2 , C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, methoxy or methylthio; p is zero or 1; R 1 is fluorine, chlorine, bromine, C 1 -C 4 -alkyl or C 1 -C 4 -haloalkyl; R 2 is hydrogen or halogen; R 3 is hydrogen, methyl or ethyl; W is O or S; with the proviso that, if a) W═O, R 1 =methyl and R 3 is hydrogen, R 2 is not fluorine, or b) W═O, n=0, m=2, p=0, R 2 and R 3 are hydrogen, R 1 is not trifluoromethyl or difluoromethyl, to processes for preparing these compounds, to compositions comprising them and to methods for using them for controlling harmful fungi.

  本发明涉及吡唑羧酰胺I，其中变量定义如下：n为零或2；m为2或3；X1为氟或氯；X2为卤素；Y为CN，NO2，C1-C4-烷基，C1-C4-卤代烷基，甲氧基或甲硫基；p为零或1；R1为氟，氯，溴，C1-C4-烷基或C1-C4-卤代烷基；R2为氢或卤素；R3为氢，甲基或乙基；W为O或S；前提是，如果a）W═O，R1=甲基且R3为氢，R2不为氟，或b）W═O，n=0，m=2，p=0，R2和R3为氢，R1不为三氟甲基或二氟甲基，则本发明还涉及制备这些化合物的方法，包括它们的组合物以及用于控制有害真菌的方法。