2,4,6-triphenyl-3-benzoyl-2,3,4,5-tetrahydropyridazine | 27241-81-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4,6-triphenyl-3-benzoyl-2,3,4,5-tetrahydropyridazine
• 英文别名: phenyl-(2,4,6-triphenyl-2,3,4,5-tetrahydro-pyridazin-3-yl)-methanone；3-Benzoyl-2,4,6-triphenyl-2,3,4,5-tetrahydropyridazine；phenyl-(2,4,6-triphenyl-4,5-dihydro-3H-pyridazin-3-yl)methanone
• CAS: 27241-81-2
• 化学式: C₂₉H₂₄N₂O
• 分子量: 416.522
• InChiKey: LRHNOYSPZYYXPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  32.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,3,5-triphenyl-2-chloropentane-1,5-dione 以 乙醇 、 溶剂黄146 为溶剂， 反应 15.0h， 生成 2,4,6-triphenyl-3-benzoyl-2,3,4,5-tetrahydropyridazine
  参考文献：
  名称：

  Transformations of stereoisomeric 2-chloro-3-R-pentane-1,5-diones in reaction with phenylhydrazine

  摘要：

  Monophenylhydrazones were prepared from three monochloro derivatives of arylaliphatic 1,5-diketones, and some their transformations were investigated. The monophenyihydrazones formed regiospecifically, and the direction of the reaction was governed by the substituent attached to C-3 atom in the initial chlorodiketones. C Formerly unknown products of transformations suffered by monophenylhydrazones obtained were described: 2-amino-1,3-diphenyl-3-(2-phenylindolyl-3)-propan-1-one, 3-benzoyl-2,4,6-triphenl-2,3,4,5-tetrahydropyridazine, and 3-methyl-1,5-diphenyl-5-phenylazopent-4-en-1-one.

  DOI：

  10.1134/s1070428007020108