tert-butyl (S)-4-{2-(2-benzoylphenyl-amino)-3-[3'-(3-heptyl-l-methylureido) biphenyl-4-yl] propionyl} PIPERAZINE-1-CARBOXYLATE | 692258-09-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tert-butyl (S)-4-{2-(2-benzoylphenyl-amino)-3-[3'-(3-heptyl-l-methylureido) biphenyl-4-yl] propionyl} PIPERAZINE-1-CARBOXYLATE
• 英文别名: tert-butyl 4-[(2S)-2-(2-benzoylanilino)-3-[4-[3-[heptylcarbamoyl(methyl)amino]phenyl]phenyl]propanoyl]piperazine-1-carboxylate
• CAS: 692258-09-6
• 化学式: C₄₆H₅₇N₅O₅
• 分子量: 759.989
• InChiKey: CBWOQYYZEJFARP-RWYGWLOXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.7
• 重原子数：
  56
• 可旋转键数：
  17
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  111
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
  申请人：GALDERMA RESEARCH & DEVELOPMENT

  公开号：EP1575911B1

  公开（公告）日：2010-01-13
• BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
  申请人：Galderma Research & Development, S.N.C.

  公开号：EP1575911A2

  公开（公告）日：2005-09-21
• [EN] NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARgamma TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS<br/>[FR] NOUVEAUX COMPOSES BIAROMATIQUES QUI ACTIVENT LES RECEPTEURS TYPE PPAR DOLLAR G(G), ET LEUR UTILISATION DANS LES COMPOSITIONS COSMETIQUES ET PHARMACEUTIQUES
  申请人：GALDERMA RES & DEV

  公开号：WO2004046091A2

  公开（公告）日：2004-06-03

  The invention relates to novel biaromatic compounds which correspond to the general formula (I), and also to a process for preparing them and to their use in pharmaceutical compositions intended for use in human or veterinary medicine (in dermatology, and also in the field of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or alternatively in cosmetic compositions.