Methylbenzamido)nicotinic acid | 1358488-78-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Methylbenzamido)nicotinic acid
• 英文别名: 2-(4-carbamoyl-4-piperidin-1-ylpiperidin-1-yl)-5-[(4-methylbenzoyl)amino]pyridine-3-carboxylic acid
• CAS: 1358488-78-4
• 化学式: C₂₅H₃₁N₅O₄
• 分子量: 465.5
• InChiKey: ZXWHESBABUHJBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  129
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Compositions and methods for treating inflammatory bowel disease
  申请人：The Broad Institute, Inc.

  公开号：US11382908B2

  公开（公告）日：2022-07-12

  Disclosed herein are compounds for the treatment of inflammatory bowel disease. Additionally, provided herein are compositions and methods for using these compounds and compositions in the treatment of inflammatory bowel disease in a subject.

  本文公开了用于治疗炎症性肠病的化合物。 此外，本文还提供了使用这些化合物和组合物治疗受试者炎症性肠病的组合物和方法。
• COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE
  申请人：Leshchiner Elizaveta

  公开号：US20200268736A1

  公开（公告）日：2020-08-27

  Disclosed herein are compounds for the treatment of inflammatory bowel disease. Additionally, provided herein are compositions and methods for using these compounds and compositions in the treatment of inflammatory bowel disease in a subject.
• [EN] COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE<br/>[FR] COMPOSITIONS ET MÉTHODES DE TRAITEMENT D'UNE MALADIE INTESTINALE INFLAMMATOIRE
  申请人：BROAD INST INC

  公开号：WO2019067530A1

  公开（公告）日：2019-04-04

  Disclosed herein are compounds for the treatment of inflammatory bowel disease. Additionally, provided herein are compositions and methods for using these compounds and compositions in the treatment of inflammatory bowel disease in a subject.