10b-Hydroxy-3-phenyl-4,6-dihydrofuro[3,2-d][2]benzoxepin-2-one | 1289403-21-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噁庚英
• 英文名称: 10b-Hydroxy-3-phenyl-4,6-dihydrofuro[3,2-d][2]benzoxepin-2-one
• 英文别名: 10b-hydroxy-3-phenyl-4,6-dihydrofuro[3,2-d][2]benzoxepin-2-one
• CAS: 1289403-21-9
• 化学式: C₁₈H₁₄O₄
• 分子量: 294.307
• InChiKey: AFRCZILJICPMHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  乙醇 、 10b-Hydroxy-3-phenyl-4,6-dihydrofuro[3,2-d][2]benzoxepin-2-one 以 氯仿 为溶剂， 反应 5.0h， 生成
  参考文献：
  名称：

  Rhodium/Chiral Diene-Catalyzed Asymmetric Cyclopolymerization of Achiral 1,8-Diynes

  摘要：

  Cyclopolymerization of nitrogen-bridged 1,8-diynes containing one terminal and one internal alkyne in the presence of a rhodium/chiral diene catalyst gave enantiomerically enriched polymers with a helix chirality that keep their chiral structures in solution. This polymerization proceeded through alternating reaction of the terminal and the internal alkynes, forming polyacetylenes with a 1,2-dialkylidene heterocyclic unit.

  DOI：

  10.1021/om200088q
• 作为产物：
  描述：

  N-[(2-ethynylphenyl)methyl]-N-(3-phenylprop-2-ynyl)aniline 在 triphenylvinyllithium 、 C₃₆H₃₆Cl₂F₈O₈Rh₂ 、 三苯基膦 、 sodium periodate 、 ruthenium (III) chloride trihydrate 作用下， 以 氟苯 、 二氯甲烷 、 水 、 乙腈 为溶剂， 反应 44.0h， 生成 10b-Hydroxy-3-phenyl-4,6-dihydrofuro[3,2-d][2]benzoxepin-2-one
  参考文献：
  名称：

  Rhodium/Chiral Diene-Catalyzed Asymmetric Cyclopolymerization of Achiral 1,8-Diynes

  摘要：

  Cyclopolymerization of nitrogen-bridged 1,8-diynes containing one terminal and one internal alkyne in the presence of a rhodium/chiral diene catalyst gave enantiomerically enriched polymers with a helix chirality that keep their chiral structures in solution. This polymerization proceeded through alternating reaction of the terminal and the internal alkynes, forming polyacetylenes with a 1,2-dialkylidene heterocyclic unit.

  DOI：

  10.1021/om200088q

文献信息

• Rhodium/Chiral Diene-Catalyzed Asymmetric Cyclopolymerization of Achiral 1,8-Diynes
  作者：Yoshitaka Ichikawa、Takahiro Nishimura、Tamio Hayashi

  DOI：10.1021/om200088q

  日期：2011.4.25

  Cyclopolymerization of nitrogen-bridged 1,8-diynes containing one terminal and one internal alkyne in the presence of a rhodium/chiral diene catalyst gave enantiomerically enriched polymers with a helix chirality that keep their chiral structures in solution. This polymerization proceeded through alternating reaction of the terminal and the internal alkynes, forming polyacetylenes with a 1,2-dialkylidene heterocyclic unit.