| 147020-86-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 147020-86-8
• 化学式: C₅₅H₅₂ClMoNO₂P₄
• 分子量: 1014.31
• InChiKey: AGIKLUYVUZJUMB-UHFFFAOYSA-M

反应信息

• 作为反应物：
  描述：

  在 CH₃I 作用下， 以74%的产率得到
  参考文献：
  名称：

  Electrosynthesis of amino acids from a molybdenum nitride via nitrogen–carbon and carbon–carbon bond formation reactions involving imides and nitrogen ylides: X-ray structure of trans-[MoCl(NCHCO₂Me)(Ph₂PCH₂CH₂PPh₂)₂]·CH₂Cl₂

  摘要：

  通过顺序生成氮-碳和碳-碳键，以及一个电化学的钼-氮键断裂步骤，确定了一条从钼氮化物trans-[MoCl(N)(Ph2PCH2CH2PPh2)2]到甘氨酸和丙氨酸的甲基酯的合成路径，其中一个关键中间体是金属氮烯trans-[MoCl(NCHCO2Me)(Ph2PCH2CH2PPh2)2]，其结构已通过晶体学方法确定。

  DOI：

  10.1039/c39920001762
• 作为产物：
  描述：

  在 (C₂H₅)3N 作用下， 以90%的产率得到
  参考文献：
  名称：

  Electrosynthesis of amino acids from a molybdenum nitride via nitrogen–carbon and carbon–carbon bond formation reactions involving imides and nitrogen ylides: X-ray structure of trans-[MoCl(NCHCO₂Me)(Ph₂PCH₂CH₂PPh₂)₂]·CH₂Cl₂

  摘要：

  通过顺序生成氮-碳和碳-碳键，以及一个电化学的钼-氮键断裂步骤，确定了一条从钼氮化物trans-[MoCl(N)(Ph2PCH2CH2PPh2)2]到甘氨酸和丙氨酸的甲基酯的合成路径，其中一个关键中间体是金属氮烯trans-[MoCl(NCHCO2Me)(Ph2PCH2CH2PPh2)2]，其结构已通过晶体学方法确定。

  DOI：

  10.1039/c39920001762

文献信息

• Ligand-centred chemistry of molybdenum organoimides. Formation of C–C bonds via generation of nitrogen ylides, stereospecific conversion of an allylimide into alkylvinyl-imides, liberation of cyanoformate or amino acid esters
  作者：Shirley A. Fairhurst、David L. Hughes、Saad K. Ibrahim、Marie-Laurence Abasq、Jean Talarmin、M. Arlete Queiros、Antonio Fonseca、Christopher J. Pickett

  DOI：10.1039/dt9950001973

  日期：——

  The range of imides trans-[MoCl(NCHR(1)R(2))(dppe)(2)](+) made from the nitride trans-[MoCl(N)(dppe)(2)] (dppe = Ph(2)PCH(2)CH(2)PPh(2), R(1) = H or organic group, R(2) = organic group) has been extended; deprotonation of the imide group at the alpha-carbon gives reactive alkenylamides which have nitrogen ylide character Mo=N+-C(-)HR} and these are attacked by electrophiles. Stepwise C-1 homologation of a methylimide to ethyl- and isopropyl-imides can be achieved by successive deprotonation and methylation steps. The crystal structure of the alkenylamide trans-[MoCl(NCHCO(2)Me)(dppe)(2)] has been determined, as has that of the imide produced directly from it by C-methylation, trans [MoClNCH(Me)CO(2)Me}(dppe)(2)](+). Deprotonation at the alpha-carbon of an allylimide complex gives a species which is regioselectively and stereospecifically attacked by electrophiles at the gamma-carbon; when the electrophile is the proton the overall reaction corresponds to a 1,3-prototropic rearrangement of the allylimide to the E-methylvinylimide. Electroreduction of imides in the presence of a source of protons releases the free amine; in this way esters of the amino acids glycine and DL-alanine have been:synthesised. Two protons-can be removed by base from imides with electron-withdrawing ester substituents and free cyanoformate esters are released from-the metal centre by substitution with dinitrogen or CO.
• A dibasic carbon centre: kinetic and thermodynamic studies on the deprotonation of trans-[MoCl(NCH2CO2Me)(Ph2PCH2CH2PPh2)2]+
  作者：Richard A. Henderson、Saad K. Ibrahim、Christopher J. Pickett

  DOI：10.1039/c39930000392

  日期：——

  A kinetic and thermodynamic analysis of the reaction between trans-[MoCl(NCHRCO2Me)(dppe)2]+(R = H or Me, dppe = Ph2PCH2CH2PPh2) and MeO– shows that when R = H both NCH2 protons are ionisable, with the pKas of trans-[MoCl(NCH2CO2Me)(ppe)2]+(pKa= 11.2) and trans-[MoCl(NCHCO)2Me(dppe)2](pKa= 11.5) being remarkably similar.