N-[(E)-2-phenylethenyl]-N-phenylmethoxyacetamide | 1007122-28-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(E)-2-phenylethenyl]-N-phenylmethoxyacetamide
• CAS: 1007122-28-2
• 化学式: C₁₇H₁₇NO₂
• 分子量: 267.327
• InChiKey: YXZUUBYNYKJBHG-OUKQBFOZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  乙酰氯 、 2-phenylacetaldehyde O-benzyl oxime 以 二氯甲烷 为溶剂， 反应 24.0h， 以85%的产率得到N-[(E)-2-phenylethenyl]-N-phenylmethoxyacetamide
  参考文献：
  名称：

  Synthesis of N-hydroxyenamide, a potential precursor of chartelline

  摘要：

  In our synthetic plan for chartelline A-C, a compound including N-hydroxyenamide moiety was designed as an important intermediate. Synthesis of the required N-hydroxyenamide by N-acylation of a suitable oxime derivative has been developed using model compounds. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.155

文献信息

• Synthesis of N-hydroxyenamide, a potential precursor of chartelline
  作者：Shigeo Kajii、Toshio Nishikawa、Minoru Isobe

  DOI：10.1016/j.tetlet.2007.11.155

  日期：2008.1

  In our synthetic plan for chartelline A-C, a compound including N-hydroxyenamide moiety was designed as an important intermediate. Synthesis of the required N-hydroxyenamide by N-acylation of a suitable oxime derivative has been developed using model compounds. (c) 2007 Elsevier Ltd. All rights reserved.