3-(benzyloxy)decanoic acid | 1194813-52-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(benzyloxy)decanoic acid
• 英文别名: 3-Phenylmethoxydecanoic acid
• CAS: 1194813-52-9
• 化学式: C₁₇H₂₆O₃
• 分子量: 278.392
• InChiKey: MXMSCQLNNCTUKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  20
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  ethyl (2S,3R)-2,3-dihydroxy-5-phenylmethoxydodecanoate 在 四丙基高钌酸铵 、 N-甲基吗啉氧化物 作用下， 以 二氯甲烷 为溶剂， 以83%的产率得到3-(benzyloxy)decanoic acid
  参考文献：
  名称：

  Tetrapropylammonium Perruthenate Catalyzed Glycol Cleavage to Carboxylic (Di)Acids

  摘要：

  A new method to accomplish glycol cleavage to carboxylic (di)acids in one step using catalytic amounts of tetrapropylammonium perruthenate (TPAP) together with N-methylmorpholine N-Oxide (NMO) as the stoichiometric oxidant is presented. In addition to regenerating the active catalyst, the N-oxide stabilizes intermediary carbonyl hydrates and thereby shifts a crucial equilibrium. The mild oxidation protocol is applicable to a broad range of substrates providing the respective acids, diacids, or keto acids in high yields.

  DOI：

  10.1021/ol202354g

文献信息

• COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE MOLECULES
  申请人：FIRMENICH SA

  公开号：EP1460994B1

  公开（公告）日：2008-10-01
• GLYCOLIPOPEPTIDE BIOSURFACTANTS
  申请人：Croda International PLC

  公开号：EP3440179A2

  公开（公告）日：2019-02-13
• [EN] GLYCOLIPOPEPTIDE BIOSURFACTANTS<br/>[FR] BIOTENSIOACTIFS GLYCOPEPTIDIQUES
  申请人：CRODA INT PLC

  公开号：WO2017174748A2

  公开（公告）日：2017-10-12

  Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine- leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in- water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.