sulfuric acid mono[2-(5-((S)-1-aminoethyl)[1,3,4]oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] ester | 1426572-56-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: sulfuric acid mono[2-(5-((S)-1-aminoethyl)[1,3,4]oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] ester
• 英文别名: trans-sulphuric acid mono-[2-(5-((S)-1-amino-ethyl)-[1,3,4]-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]-octan-6-yl] ester；Antibacterial agent 35；[(2S,5R)-2-[5-[(1S)-1-aminoethyl]-1,3,4-oxadiazol-2-yl]-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
• CAS: 1426572-56-6
• 化学式: C₁₀H₁₅N₅O₆S
• 分子量: 333.325
• InChiKey: IIGJRSBRPZGZLI-XVMARJQXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.4
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  161
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• Pharmaceutical compositions comprising antibacterial agents
  申请人：WOCKHARDT LIMITED

  公开号：US10857138B2

  公开（公告）日：2020-12-08

  Pharmaceutical compositions comprising aztreonam or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed. (I)

  本发明公开了包含阿兹曲南或其药学上可接受的衍生物以及式(I)化合物或其立体异构体或其药学上可接受的衍生物的药物组合物。(I)
• PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENTS
  申请人：WOCKHARDT LIMITED

  公开号：US20170035740A1

  公开（公告）日：2017-02-09

  Pharmaceutical compositions comprising aztreonam or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed. (I)
• [EN] PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENTS<br/>[FR] COMPOSITIONS PHARMACEUTIQUES COMPRENANT DES AGENTS ANTIBACTÉRIENS
  申请人：WOCKHARDT LTD

  公开号：WO2015159265A1

  公开（公告）日：2015-10-22

  Pharmaceutical compositions comprising aztreonam or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed. (I)