2-methylene-5α-cholestane | 73406-77-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 2-methylene-5α-cholestane
• 英文别名: 2-Methylen-5α-cholestan
• CAS: 73406-77-6
• 化学式: C₂₈H₄₈
• 分子量: 384.689
• InChiKey: PIWBFWMUPKONDS-COZJBHHDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.66
• 重原子数：
  28.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  2-methylene-5α-cholestane 在 吡啶 、 lead(IV) acetate 、 四氧化锇 、 氯仿 、 溶剂黄146 作用下， 生成 5α-cholestan-2-one
  参考文献：
  名称：

  Characterization of Indoor Particle Sources Using Continuous Mass and Size Monitors

  摘要：

  A comprehensive indoor particle characterization study was conducted in nine Boston-area homes in 1998 in order to characterize sources of PM in indoor environments. State-of-the-art sampling methodologies were used to obtain continuous PM2.5 concentration and size distribution particulate data for both indoor and outdoor air. Study homes, five of which were sampled during two seasons, were monitored over week-long periods. Among other data collected during the extensive monitoring efforts were 24-hr elemental/organic carbon (EC/OC) particulate data as well as semi-continuous air exchange rates and time-activity information.This rich data set shows that indoor particle events tend to be brief, intermittent, and highly variable, thus requiring the use of continuous instrumentation for their characterization. In addition to dramatically increasing indoor PM2.5 concentrations, these data demonstrate that indoor particle events can significantly alter the size distribution and composition of indoor particles. Source event data demonstrate that the impacts of indoor activities are especially pronounced in the ultrafine (d(a) less than or equal to 0.1 mu m) and coarse (2.5 less than or equal to d(a) less than or equal to 10 mu m) modes. Among the sources of ultrafine particles characterized in this study are indoor ozone/terpene reactions. furthermore, EC/OC data suggest that organic carbon is a major constituent of particles emitted during indoor source events. Whether exposures to indoor-generated particles, particularly from large short-term peak events, may be associated with adverse health effects will become clearer when biological mechanisms are better known.

  DOI：

  10.1080/10473289.2000.10464154
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 一水合肼 作用下， 生成 2-methylene-5α-cholestane
  参考文献：
  名称：

  Characterization of Indoor Particle Sources Using Continuous Mass and Size Monitors

  摘要：

  A comprehensive indoor particle characterization study was conducted in nine Boston-area homes in 1998 in order to characterize sources of PM in indoor environments. State-of-the-art sampling methodologies were used to obtain continuous PM2.5 concentration and size distribution particulate data for both indoor and outdoor air. Study homes, five of which were sampled during two seasons, were monitored over week-long periods. Among other data collected during the extensive monitoring efforts were 24-hr elemental/organic carbon (EC/OC) particulate data as well as semi-continuous air exchange rates and time-activity information.This rich data set shows that indoor particle events tend to be brief, intermittent, and highly variable, thus requiring the use of continuous instrumentation for their characterization. In addition to dramatically increasing indoor PM2.5 concentrations, these data demonstrate that indoor particle events can significantly alter the size distribution and composition of indoor particles. Source event data demonstrate that the impacts of indoor activities are especially pronounced in the ultrafine (d(a) less than or equal to 0.1 mu m) and coarse (2.5 less than or equal to d(a) less than or equal to 10 mu m) modes. Among the sources of ultrafine particles characterized in this study are indoor ozone/terpene reactions. furthermore, EC/OC data suggest that organic carbon is a major constituent of particles emitted during indoor source events. Whether exposures to indoor-generated particles, particularly from large short-term peak events, may be associated with adverse health effects will become clearer when biological mechanisms are better known.

  DOI：

  10.1080/10473289.2000.10464154