cis-[Ru(2,2′:6′,2″-terpyridine)(acetonitrile)2Cl]⁺ | 118714-55-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: cis-[Ru(2,2′:6′,2″-terpyridine)(acetonitrile)2Cl]⁺
• 英文别名: cis-[Ru(tpy)(CH3CN)2Cl]⁺；cis-Ru(trpy)(CH3CN)2Cl(1+)；[RuCl(acetonitrile)2(2,2':6',2''-terpyridine)](1+)
• CAS: 118714-55-9
• 化学式: C₁₉H₁₇ClN₅Ru
• 分子量: 451.9
• InChiKey: RKCNOCPVVDAMHO-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  cis-[Ru(2,2′:6′,2″-terpyridine)(acetonitrile)2Cl]⁺ 以 吡啶 为溶剂， 生成
  参考文献：
  名称：

  Suen; Wilson; Pomerantz, Inorganic Chemistry, 1989, vol. 28, # 4, p. 786 - 791

  摘要：

  DOI：
• 作为产物：
  描述：

  trans-Ru(trpy)(py)2Cl(1+) 在 乙腈 作用下， 以 乙腈 为溶剂， 生成 cis-[Ru(2,2′:6′,2″-terpyridine)(acetonitrile)2Cl]⁺
  参考文献：
  名称：

  Suen; Wilson; Pomerantz, Inorganic Chemistry, 1989, vol. 28, # 4, p. 786 - 791

  摘要：

  DOI：

文献信息

• Synthesis of Nitrosylruthenium Complexes Containing 2,2‘:6‘,2‘ ‘-Terpyridine by Reactions of Alkoxo Complexes with Acids
  作者：Hirotaka Nagao、Keiji Enomoto、Yuuki Wakabayashi、Gen Komiya、Toshiyuki Hirano、Takao Oi

  DOI：10.1021/ic061644w

  日期：2007.2.19

  Nitrosylruthenium complexes containing 2,2':6',2"-terpyridine (terpy) have been synthesized and characterized. The three alkoxo complexes trans-(NO, OCH3), cis-(Cl, OCH3)-[RuCl(OCH3)(NO)(terpy)]PF6 ([2]PF6), trans-(NO, OC2H5), cis-(Cl, OC2H5)-[RuCl(OC2H5)(NO)(terpy)]PF6 ([3]PF6), and [RuCl(OC3H7)(NO)(terpy)]PF6 ([4]PF6) were synthesized by reactions of trans-(Cl, Cl), cis-(NO, Cl)-[RuCl2(NO)(terpy)]PF6

  [3] PF6与三氟甲磺酸在CH3CN中的反应得到反式-（NO，Cl），顺-（CH3CN，Cl）-[RuCl（CH3CN）（NO）（terpy）] 2+（[6] 2+）回流条件。通过X射线晶体结晶法确定[3] PF6，[4] PF6.CH3CN，[5] CF3SO3和[6]（PF6）2的结构。
• Reactions of [RuCl2(NO)(terpy)]+ (terpy = 2,2′ : 6′,2″-terpyridine) with mono anions such as NO2–, Br– and N3–, and structural studies on terpyridineruthenium having a nitrosyl ligand
  作者：Toshiyuki Hirano、Koji Ueda、Masao Mukaida、Hirotaka Nagao、Takao Oi

  DOI：10.1039/b101546j

  日期：——

  [RuCl2(NO)(terpy)]PF6 ([1]PF6) has been synthesized by the reaction of K2[RuCl5(NO)] with terpy and characterized by single-crystal X-ray crystallography. [1]PF6 has a structure in which the two chloro ligands are located trans to each other with the nitrosyl ligand on the plane of the terpy ligand. Reactions of [1]PF6 with mono anions such as NO2−, Br− and N3− have been investigated. Its reactions with NO2− in H2O and CH3OH afford nitrosylterpyridineruthenium complexes, [Ru(OH)(NO2)(NO)(terpy)]PF6 ([2]PF6) and [RuCl(OCH3)(NO)(terpy)]PF6 ([3]PF6), respectively, whose geometrical configurations differ from that of [1]+. The Br−-substituted complex of [1]+, [RuBr2-(NO)(terpy)]PF6 ([4]PF6), and two solvated complexes, [RuCl2(CH3CN)(terpy)] ([5]) and [RuCl(CH3CN)2(terpy)]PF6 ([6]PF6), have been formed in its reactions with Br− and N3−. Structures of [2]PF6, [3]PF6 and [4]PF6 have been determined by singal-crystal X-ray crystallography and compared with each other.

  [RuCl2(NO)(terpy)]PF6 ([1]PF6) 通过 K2[RuCl5(NO)] 与 terpy 反应合成，并通过单晶 X 射线晶体学表征。 [1]PF6具有这样的结构，其中两个氯配体与亚硝酰配体位于三联配体的平面上彼此反式。研究了 [1]PF6 与单阴离子如 NO2-、Br- 和 N3- 的反应。它与 H2O 和 CH3OH 中的 −反应，生成亚硝酰基三联吡啶钌络合物，[Ru(OH)( )(NO)(terpy)]PF6 ([2]PF6) 和 [RuCl(OCH3)(NO)(terpy)]PF6 ([3]PF6)，其几何构型与[1]+不同。 [1]+ 的 Br-取代络合物 [RuBr2-(NO)(terpy)]PF6 ([4]PF6) 和两个溶剂化络合物 [RuCl2(CH3CN)(terpy)] ([5])和[RuCl(CH3CN)2(terpy)]PF6 ([6]PF6)在与Br-和N3-的反应中形成。通过单晶X射线晶体学确定了[2]PF6、[3]PF6和[4]PF6的结构并进行了相互比较。
• Synthesis, spectroscopic characterization, electrochemical and photochemical properties of ruthenium(II) polypyridyl complexes with a tertiary amine ligand
  作者：Hideo Konno、Yuji Ishii、Kazuhiko Sakamoto、Osamu Ishitani

  DOI：10.1016/s0277-5387(01)00969-x

  日期：2002.1

  spectroscopic, electrochemical and photochemical properties of these complexes are studied and compared to those of the corresponding primary-amine complexes [Ru(bpy)2(AEPy)]2+ (1b) and [Ru(tpy)(AEPy)Cl]+ (3b) where AEPy=2-(2′-aminoethyl)-pyridine. The MLCT bands in the UV–Vis absorption spectra of the tertiary-amine complexes were blue-shifted (8–9 nm), and their redox potentials for the RuII/III couples were

  合成了一系列具有叔脂肪胺配体[Ru（4,4'-X 2 bpy）2（DMAEPy）] 2+（1a ; X = H，2 ; X = CF 3的钌（II）聚吡啶配合物），[Ru（tpy）（N–N）Cl] +（3a ; N–N = DMAEPy，3c ; N–N = DEAEPy）和[Ru（tpy）（DMAEPy）（MeCN）] 2+（4）其中DMAEPy = 2-（2'-二甲基氨基乙基）-吡啶，DEAEPy = 2-（2'-二乙基氨基乙基）-吡啶，tpy = 2,2'：6'，2''-吡啶和bpy = 2,2'-联吡啶。研究了这些配合物的光谱，电化学和光化学性质，并与相应的伯胺配合物[Ru（bpy）2（AEPy）] 2+（1b）和[Ru（tpy）（AEPy）Cl] +（3b），其中AEPy = 2-（2'-氨基乙基）-吡啶。叔胺配合物在UV-Vis吸收光谱中的MLCT谱带发生蓝移（8–9 nm），并且与Ru
• Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex
  作者：Mark A. Sgambellone、Amanda David、Robert N. Garner、Kim R. Dunbar、Claudia Turro

  DOI：10.1021/ja4045604

  日期：2013.7.31

  The series [Ru(tpy)(CH3CN)(3)](2+) (1), cis-[Ru(tpy)-(CH3CN)(2)C1](+) (2), and [Ru(tpy)(5CNU)(3)](2+) (3), where tpy = 2,2':6',2 ''-terpyridine and SCNU = 5-cyanouracil, was synthesized, and their photochemical properties were investigated for use as potential photodynamic therapy (PDT) agents. When irradiated with visible light, 1-3 exhibit efficient exchange of the axial CH3CN or SCNU ligand with H2O solvent molecules. Complexes 1-3 also exhibit photoinitiated binding to DNA when irradiated with lambda(irr) >= 395 nm light, and DNA binding can be accessed for 2 with lambda(irr) > 645 am, well within the PDT window. Since 3 binds DNA and simultaneously releases biologically active 5CNU, it has the potential to be a dual-action therapeutic agent. Indeed, 3 is cytotoxic upon irradiation with visible light, whereas 1 is not under similar experimental conditions. The lack of toxicity imparted by 1 is explained by the exchange of only one CH3CN ligand in the complex under the irradiation conditions used for the cellular studies. Strategies are being sought to increase the quantum yields of ligand exchange and the cellular penetration of these compounds.