Benzoylchlorsulfat | 56114-23-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzoylchlorsulfat
• 英文别名: Chlorosulfonylphenylcarboxylic acid；chlorosulfonyl benzoate
• CAS: 56114-23-9
• 化学式: C₇H₅ClO₄S
• mdl: MFCD19200757
• 分子量: 220.633
• InChiKey: JQRUYENXNMGOFK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  68.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  苯甲酰氯 在 三氧化硫 作用下， 生成 Benzoylchlorsulfat
  参考文献：
  名称：

  Addition of sulfur trioxide to acid halides and esters

  摘要：

  DOI：

  10.1021/jo00908a018

文献信息

• Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers
  申请人：Starnes Herbert William

  公开号：US20050049307A1

  公开（公告）日：2005-03-03

  Organic thiol compounds based on pentaerythritol and dipentaerythritol are described herein. More specifically, the compounds of the present invention are mixed esters of pentaerythritol and dipentaerythritol having at least one sulfhydryl group and preferably a plurality of sulfhydryl groups as well as at least one non-thiol-containing group. The organic thiol compounds are utilized to plasticize and/or heat stabilize halogen-containing polymer compositions especially poly(vinyl chloride) compositions. The compositions are substantially free or free of metal-based stabilizers, Lewis acids and terpenes. The compounds of the present invention are ideally utilized in polymers normally susceptible to deterioration and color change which can occur during processing of the polymer or exposure of the polymer to certain environments and surprisingly also serve as excellent plasticizers.

  本文描述了基于对羟基甲苯和二对羟基甲苯的有机硫醇化合物。更具体地说，本发明的化合物是对羟基甲苯和二对羟基甲苯的混合酯，具有至少一个巯基和最好是多个巯基，以及至少一个非巯基含有基团。这些有机硫醇化合物被用于增塑和/或热稳定含卤素聚合物组合物，特别是聚氯乙烯组合物。这些组合物基本上不含或不含金属基稳定剂、路易斯酸和萜类物质。本发明的化合物在通常容易恶化和变色的聚合物中得到理想应用，这种恶化和变色可能发生在聚合物加工过程中或聚合物暴露于某些环境中，并且令人惊讶地还可作为优秀的增塑剂。
• [EN] HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS<br/>[FR] COMPOSES SULFONYLE ARYLE OU HETEROARYLE D'ACIDE HYDROXAMIQUE
  申请人：SEARLE & CO

  公开号：WO2000069819A1

  公开（公告）日：2000-11-23

  A sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound in an MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity. A contemplated compound corresponds in structure to formula (a) wherein W and the R groups are defined elsewhere.

  本发明涉及一种磺酰基芳香族或杂芳香族环羟肟酸化合物，该化合物在抑制基质金属蛋白酶活性方面具有作用，还涉及一种治疗过程，包括向患有与病理基质金属蛋白酶活性相关的病症的宿主中投与考虑到的磺酰基芳香族或杂芳香族环羟肟酸化合物，其剂量足以抑制MMP酶活性。 考虑到的化合物在结构上对应于公式（a），其中W和R基在其他地方定义。
• A process for the preparation of an azidosulphonylbenzoic acid
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0212741A1

  公开（公告）日：1987-03-04

  The invention relates to a process for the preparation of an azidosulphonylbenzoic acid which comprises reacting a water-­soluble salt of a chlorosulphonylbenzoic acid with hydrazine (N₂H₄) in an aqueous medium, reacting the obtained hydrazino­sulphonylbenzoic acid salt with nitrous acid in the same aqueous medium, acidifying the resulting aqueous solution comprising the azidosulphonylbenzoic acid salt, to precipitate the azidosul­phonylbenzoic acid and separating the azidosulphonylbenzoic acid. The process is a one-pot process, which differs from a known process in that the intermediate, being the hydrazino­sulphonylbenzoic acid salt, is not isolated.

  本发明涉及一种偶氮磺酰基苯甲酸的制备工艺，该工艺包括在水介质中使氯磺酰基苯甲酸的水溶性盐与肼(N₂H₄)反应、在相同的水介质中使得到的肼磺酰基苯甲酸盐与亚硝酸反应，酸化得到的包含叠氮磺酰基苯甲酸盐的水溶液，沉淀叠氮磺酰基苯甲酸，分离叠氮磺酰基苯甲酸。该工艺是一种单锅工艺，它与已知工艺的不同之处在于中间体（即肼基磺酰基苯甲酸盐）没有分离出来。
• SULFONYL DIVALENT ARYL OR HETEROARYL HYDROXAMIC ACID COMPOUNDS
  申请人：MONSANTO COMPANY

  公开号：EP0973392A1

  公开（公告）日：2000-01-26
• EP0973392A4
  申请人：——

  公开号：EP0973392A4

  公开（公告）日：2001-05-02