trans-RuH(phenolato)(2,3-diamino-2,3-dimethylbutane)(PPh3)2*(phenol) | 915285-60-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans-RuH(phenolato)(2,3-diamino-2,3-dimethylbutane)(PPh3)2*(phenol)
• 英文别名: trans-RuH(OPh)(tmen)(PPh3)2*HOPh
• CAS: 915285-60-8
• 化学式: C₆H₆O*C₄₈H₅₂N₂OP₂Ru
• 分子量: 930.084
• InChiKey: DPMUXSSMLAVCIO-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  trans-RuH(phenolato)(2,3-diamino-2,3-dimethylbutane)(PPh3)2 、 苯酚 以 正己烷 、 苯 为溶剂， 生成 trans-RuH(phenolato)(2,3-diamino-2,3-dimethylbutane)(PPh3)2*(phenol)
  参考文献：
  名称：

  Probing the Effect of the Ligand X on the Properties and Catalytic Activity of the Complexes RuHX(diamine)(PPh₃)₂ (X = OPh, 4-SC₆H₄OCH₃, OPPh₂, OP(OEt)₂, CCPh, NCCHCN, CH(COOMe)₂; diamine = 2,3-Diamino-2,3-dimethylbutane, (R,R)-1,2-Diaminocyclohexane)

  摘要：

  The reactivity of the ruthenium-amido bond in RuH(NH2CMe2CMe2NH)(PPh3)(2) (1) toward weak acids HX and the influence of the X group on the catalytic activity of the resulting complex are explored here. Complex 1 reacts with the weak acids HX (X = OPh, 4-SC6H4OMe, OPPh2, OP(OEt)(2), CCPh, NCCHCN, CH(COOMe)(2)) to form complexes of the type RuHX(tmen)(PPh3)(2) (tmen = 2,3-diamino-2,3- dimethylbutane). The complexes with X = PhOH center dot center dot center dot OPh, 4-SC6H4OMe, OP(OEt)(2), CCPh, CH-( COOMe) 2 have been characterized by X-ray crystallography. The X group is situated trans to the hydride in all cases and is bonded to ruthenium via the donor atoms O, S, P, C, and O, respectively. The phenol in the phenoxide adduct RuH(PhOH center dot center dot center dot OPh)(tmen)(PPh3)(2) bridges via hydrogen bonds between the alkoxide oxygen and an amino hydrogen to form a six-membered RuO center dot center dot center dot HO center dot center dot center dot HN ring. One carbonyl oxygen of the malonate bonds to the Ru, while the other accepts a hydrogen bond from an amino hydrogen. The analogous complexes RuHX(dach)(PPh3)(2) (dach) (R,R)-1,2-diaminocyclohexane) were synthesized by the reaction of RuHCl(dach)(PPh3)(2) (2) with an equimolar amount of potassium tert-butoxide and HX. For all of the complexes the Ru-H vibrational frequency and the H-1 NMR chemical shift of Ru-H correlate with the electronegativity of the trans atom X. The amido complex 1 and the complexes with X = CH(COOMe)(2) and OPh are active catalysts for the Michael addition of dimethyl malonate to 2-cyclohexen-1-one. RuH(NCCHCN)(tmen)(PPh3)(2) reacts with the Michael acceptor 2-cyclohexen-1-one to give RuH(NCC(C6H9O)CN)(tmen)(PPh3)(2), a trapped Michael adduct that has been characterized by X-ray crystallography. On the basis of these observations a catalytic cycle for the Michael addition reactions is proposed that involves the addition of the C-H bond of the Michael donor to the Ru-N bond followed by attack on the Michael acceptor and elimination of the Michael adduct, possibly by a 1,3- proton migration as observed for the malononitrile adduct. Only the complexes with X = H, CCPh are catalysts or precatalysts for the hydrogenation of neat acetophenone to 1-phenylethanol in the absence of added base under 10 atm of H-2 at 20 degrees C. Evidence is provided that the phenylacetylide complexes are precatalysts that are converted to the active trans-dihydride catalysts ( X = H).

  DOI：

  10.1021/om060661q