4-anthracen-9-ylmethyl-(3-carboxy-propyl)aminobutyric acid | 1379474-05-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 4-anthracen-9-ylmethyl-(3-carboxy-propyl)aminobutyric acid
• 英文别名: 4-[Anthracen-9-ylmethyl(3-carboxypropyl)amino]butanoic acid；4-[anthracen-9-ylmethyl(3-carboxypropyl)amino]butanoic acid
• CAS: 1379474-05-1
• 化学式: C₂₃H₂₅NO₄
• 分子量: 379.456
• InChiKey: NZQAAEXTWNURGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  77.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  9-蒽甲醛 在 sodium tetrahydroborate 、 水 、 sodium hydride 、 sodium hydroxide 作用下， 以 甲醇 、 乙醇 、 二氯甲烷 、 乙腈 为溶剂， 反应 45.33h， 生成 4-anthracen-9-ylmethyl-(3-carboxy-propyl)aminobutyric acid
  参考文献：
  名称：

  Fluorescence PET (photo-induced electron transfer) sensor for water based on anthracene-amino acid

  摘要：

  An anthracene-amino acid system with two carboxyl groups has been designed and synthesized as a new class of fluorescence PET (photo-induced electron transfer) sensor for detection of water in organic solvents. An enhancement in fluorescence is observed with increasing water content in 1,4-dioxane, THF, acetonitrile and ethanol, which is attributable to the suppression of PET by the intramolecular proton transfer of the carboxyl proton to the amino group. The detection limit and quantitation limit are, respectively, 0.1 and 0.3 wt% for 1.4-dioxane, 0.4 and 1.2 wt% for THE, 0.1 and 0.3 wt% for acetonitrile and 0.1 and 0.3 wt% for ethanol. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jphotochem.2011.04.035

文献信息

• Fluorescence PET (photo-induced electron transfer) sensor for water based on anthracene-amino acid
  作者：Yousuke Ooyama、Ai Matsugasako、Tomoya Nagano、Kazuyuki Oka、Kohei Kushimoto、Kenji Komaguchi、Ichiro Imae、Yutaka Harima

  DOI：10.1016/j.jphotochem.2011.04.035

  日期：2011.7

  An anthracene-amino acid system with two carboxyl groups has been designed and synthesized as a new class of fluorescence PET (photo-induced electron transfer) sensor for detection of water in organic solvents. An enhancement in fluorescence is observed with increasing water content in 1,4-dioxane, THF, acetonitrile and ethanol, which is attributable to the suppression of PET by the intramolecular proton transfer of the carboxyl proton to the amino group. The detection limit and quantitation limit are, respectively, 0.1 and 0.3 wt% for 1.4-dioxane, 0.4 and 1.2 wt% for THE, 0.1 and 0.3 wt% for acetonitrile and 0.1 and 0.3 wt% for ethanol. (C) 2011 Elsevier B.V. All rights reserved.