1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-6-(pyridine-2-carbonyl)-1H-pyrimidine-2,4-dione | 82145-17-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-6-(pyridine-2-carbonyl)-1H-pyrimidine-2,4-dione
• CAS: 82145-17-3
• 化学式: C₁₈H₁₉N₃O₇
• 分子量: 389.365
• InChiKey: DOKBLIXBFHQEGJ-RAEVTNRLSA-N

反应信息

• 作为反应物：
  描述：

  1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-6-(pyridine-2-carbonyl)-1H-pyrimidine-2,4-dione 在 三乙胺 作用下， 以 吡啶 、 氯仿 为溶剂， 生成
  参考文献：
  名称：

  First exceptions to the "Imbach rule" for .BETA.-D-ribofuranosyl nucleosides.

  摘要：

  Introduction of an anisotropic substituent to the C-6 position of 2', 3'-O-isopropylideneuridine altered the differences in the chemical shift between the methyl signals (Δδ Me) of the isopropylidene group. Thus, exceptions to Imbach's criterion for β-D-ribofuranosyl nucleosides have now been observed for the first time.

  DOI：

  10.1248/cpb.30.1117