4-(3-乙基苯胺基)-4-氧代丁酸 | 550312-50-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(3-乙基苯胺基)-4-氧代丁酸
• 中文别名: 4-[(3-乙基苯基)氨基]-4-氧代丁酸
• 英文名称: 4-[(3-Ethylphenyl)amino]-4-oxobutanoic acid
• 英文别名: 4-(3-ethylanilino)-4-oxobutanoic acid
• CAS: 550312-50-0
• 化学式: C₁₂H₁₅NO₃
• mdl: MFCD01351263
• 分子量: 221.25
• InChiKey: IZJIRCVZHFGXPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2924299090

文献信息

• SULFONYLETHYL PHOSPHORODIAMIDATES
  申请人：Allen R. David

  公开号：US20080039429A1

  公开（公告）日：2008-02-14

  Sulfonylethyl and thioethyl phosphorodiamidates, their preparation and intermediates in their preparation, formulations containing them, and their pharmaceutical use. The compounds are useful for treating cancer, alone and in combination with other anticancer therapies.

  Sulfonylethyl和thioethyl磷酰二胺酸酯，它们的制备及其制备中间体，含有它们的制剂，以及它们的药物用途。这些化合物可用于治疗癌症，单独或与其他抗癌疗法结合使用。
• BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS
  申请人：Sattigeri Jitendra A.

  公开号：US20110166088A1

  公开（公告）日：2011-07-07

  The present invention provides Gyrase B and/or Topoisomerase IV par E inhibitors, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed by gram positive, gram negative and anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Pseudomonas spp., Acenetobacter spp., Moraxalla spp., Chlamydia spp., Mycoplasma spp., Legionella spp., Ktycobacterium spp., Helicobacter, Clostridium spp., Bacteroides spp., Corynebacterium, Bacillus spp., Enterobactericeae,’ ( E. coli, Klebsiella spp., Proteus spp., etc.) or any combination thereof. Also provided, are processes for preparing compounds disclosed herein, pharmaceutical compositions containing compounds disclosed herein, and methods of treating bacterial infections. (Formula)
• US7262182B2
  申请人：——

  公开号：US7262182B2

  公开（公告）日：2007-08-28
• US8093231B2
  申请人：——

  公开号：US8093231B2

  公开（公告）日：2012-01-10