[Rh(2-(p-tolyl)pyridinato)2(4,7-dichloro-2,9-dimethyl-1,10-phenanthroline)]PF6 | 1615240-64-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: [Rh(2-(p-tolyl)pyridinato)2(4,7-dichloro-2,9-dimethyl-1,10-phenanthroline)]PF6
• 英文别名: [Rh(2-(p-tolyl)pyridinato)₂(4,7-dichloro-2,9-dimethyl-1,10-phenanthroline)]PF₆；[Rh(ptpy)₂(ddmp)]PF₆
• CAS: 1615240-64-6
• 化学式: C₃₈H₃₀Cl₂N₄Rh*F₆P
• 分子量: 861.459
• InChiKey: JEMZCWRNJZYODF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  六氟磷酸钾 、 [{Rh(μ-Cl)(2-(p-tolyl)pyridinato)2}2] 、 4,7-dichloro-2,9-dimethyl-1,10-phenanthroline 以 甲醇 、 二氯甲烷 、 水 为溶剂， 反应 2.0h， 以50.4%的产率得到[Rh(2-(p-tolyl)pyridinato)2(4,7-dichloro-2,9-dimethyl-1,10-phenanthroline)]PF6
  参考文献：
  名称：

  Photophysical and biological characterization of new cationic cyclometalated M(III) complexes of rhodium and iridium

  摘要：

  Synthesis and characterization of new cyclometalated complex salts [M(ptpy)(2)(ddmp)]PF6 (M = Rh, 1; M = Ir, 2; ptpy = 2-(p-tolyl)pyridinato; ddmp = 4,7-dichloro-2,9-dimethyl-1,10-phenanthroline) is described. Compounds 1 and 2 were obtained by the reaction of ddmp with the complexes [(M(mu-Cl)(ptpy)(2)}(2)] (M = Rh, Ir) in a mixture of CH2Cl2/MeOH/H2O under reflux conditions. The compounds 1 and 2 crystallized from dichloromethane/chloroform/hexane in the triclinic space group P (1) over bar and their molecular structures were confirmed by single-crystal X-ray diffraction. Compound 2 exhibits strong yellow phosphorescence in a polymer matrix and in solution at ambient temperature. Both compounds display significant cytotoxicity against human cancer cell lines with the IC50 values in the high nano-molar range. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2014.04.031