2-Methyl-6-pyrrolidino-hept-2-en | 4730-13-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 2-Methyl-6-pyrrolidino-hept-2-en
• 英文别名: 1-(6-Methylhept-5-en-2-yl)pyrrolidine
• CAS: 4730-13-6
• 化学式: C₁₂H₂₃N
• 分子量: 181.321
• InChiKey: IZQFJDVUSINQKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Inhibitors Of Cognitive Decline
  申请人：Rishton Gilbert M.

  公开号：US20080193574A1

  公开（公告）日：2008-08-14

  Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
• Inhibitors of cognitive decline
  申请人：Rishton Gilbert M.

  公开号：US20110111068A1

  公开（公告）日：2011-05-12

  Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
• US7723377B2
  申请人：——

  公开号：US7723377B2

  公开（公告）日：2010-05-25
• [EN] INHIBITORS OF COGNITIVE DECLINE<br/>[FR] INHIBITEURS DU DÉCLIN COGNITIF
  申请人：CALIFORNIA STATE UNIVERSITY CH

  公开号：WO2008042755A2

  公开（公告）日：2008-04-10

  [EN] Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
  [FR] L'invention concerne des composés qui sont des médicaments candidats du système nerveux central pour traiter le déclin cognitif, et plus particulièrement la maladie d'Alzheimer. L'invention concerne également des méthodes de traitement, d'inhibition et/ou de diminution du déclin cognitif et de la maladie d'Alzheimer au moyen d'un dérivé d'huile de gingembre. L'invention concerne enfin un procédé de conditionnement d'extraits biologiques, tels qu'un extrait de plante médicinale, au moyen d'un processus d'amination réductrice pour donner des dérivés contenant de l'azote.