Triphenyl-[(2,3,5-trifluoro-7,8lambda4-dithia-9-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-8-yl)imino]-lambda5-phosphane | 1274916-62-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Triphenyl-[(2,3,5-trifluoro-7,8lambda4-dithia-9-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-8-yl)imino]-lambda5-phosphane
• 英文别名: triphenyl-[(2,3,5-trifluoro-7,8λ4-dithia-9-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-8-yl)imino]-λ5-phosphane
• CAS: 1274916-62-9
• 化学式: C₂₄H₁₆F₃N₂PS₂
• 分子量: 484.505
• InChiKey: BLGOAOAHJSUDJM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  69.2
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  Triphenyl-[(2,3,5-trifluoro-7,8lambda4-dithia-9-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-8-yl)imino]-lambda5-phosphane 以 角鲨烷 为溶剂， 反应 0.08h， 生成
  参考文献：
  名称：

  Interaction of 1,3,2,4-Benzodithiadiazines and Their 1-Se Congeners with Ph₃P and Some Properties of the Iminophosphorane Products

  摘要：

  Interaction between Ph3P and 1,3,2,4-benzodithiadiazine (I); its 6,7-difluoro (2), 5,6,8-trifluoro (3) and 5,6,7,8-tetrafluoro (4) derivatives; and 5,6,8-trifluoro-3,1,2,4-benzothiaselenadiazine (5) proceeded via a 1:1 condensation to give Ph3P=N-R iminophosphoranes (1a-5a, R = corresponding 1,2,3-benzodichalcogenazol-2-yls), which are inaccessible by general approaches based on the Staudinger and Kirsanov reactions. In contrast, neither Ph3As nor Ph3Sb reacted with 1 and 4. Molecular structures of 1a-5a and 5 were confirmed by X-ray diffraction (XRD). The crystals formed by chiral molecules of 2a-5a were racemic, whereas the crystal of la was formed by a single enantiomer. In all Of the Ph3P=N-R derivatives, one of the Ph rings is oriented face-to-face to the hetero ring, R. Upon heating to similar to 120 degrees C in squalane (1a, 3a, 4a) or dissolving in chloroform at ambient temperatures (1a, 2a, 4a) the Ph3P=N-R derivatives generated the 1,2,3-benzodithiazolyls (1b-4b, respectively) whose identity was confirmed by electron paramagnetic resonance (EPR). 2,1,3-Benzothiaselenazolyls 5b and 6b were detected by EPR as the main paramagnetic products of solution thermolysis of 5 and its 5,6,7,8-tetrafluoro congener (6), respectively. Passing a chloroform solution of 4a through silica column unexpectedly gave 5-6-6-6 tetracyclic (9) and 6-10-6 tricyclic (10) sulfur-nitrogen compounds, which were 'characterized by XRD.

  DOI：

  10.1021/ic102565x
• 作为产物：
  描述：

  三苯基膦 、 5,6,8-trifluoro-1,3λ⁴δ²,2,4-benzodithiadiazine 以 甲苯 为溶剂， 反应 1.5h， 以52%的产率得到Triphenyl-[(2,3,5-trifluoro-7,8lambda4-dithia-9-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-8-yl)imino]-lambda5-phosphane
  参考文献：
  名称：

  Interaction of 1,3,2,4-Benzodithiadiazines and Their 1-Se Congeners with Ph₃P and Some Properties of the Iminophosphorane Products

  摘要：

  Interaction between Ph3P and 1,3,2,4-benzodithiadiazine (I); its 6,7-difluoro (2), 5,6,8-trifluoro (3) and 5,6,7,8-tetrafluoro (4) derivatives; and 5,6,8-trifluoro-3,1,2,4-benzothiaselenadiazine (5) proceeded via a 1:1 condensation to give Ph3P=N-R iminophosphoranes (1a-5a, R = corresponding 1,2,3-benzodichalcogenazol-2-yls), which are inaccessible by general approaches based on the Staudinger and Kirsanov reactions. In contrast, neither Ph3As nor Ph3Sb reacted with 1 and 4. Molecular structures of 1a-5a and 5 were confirmed by X-ray diffraction (XRD). The crystals formed by chiral molecules of 2a-5a were racemic, whereas the crystal of la was formed by a single enantiomer. In all Of the Ph3P=N-R derivatives, one of the Ph rings is oriented face-to-face to the hetero ring, R. Upon heating to similar to 120 degrees C in squalane (1a, 3a, 4a) or dissolving in chloroform at ambient temperatures (1a, 2a, 4a) the Ph3P=N-R derivatives generated the 1,2,3-benzodithiazolyls (1b-4b, respectively) whose identity was confirmed by electron paramagnetic resonance (EPR). 2,1,3-Benzothiaselenazolyls 5b and 6b were detected by EPR as the main paramagnetic products of solution thermolysis of 5 and its 5,6,7,8-tetrafluoro congener (6), respectively. Passing a chloroform solution of 4a through silica column unexpectedly gave 5-6-6-6 tetracyclic (9) and 6-10-6 tricyclic (10) sulfur-nitrogen compounds, which were 'characterized by XRD.

  DOI：

  10.1021/ic102565x

文献信息

• Interaction of 1,3,2,4-Benzodithiadiazines and Their 1-Se Congeners with Ph₃P and Some Properties of the Iminophosphorane Products
  作者：Alexander Yu. Makarov、Vladimir V. Zhivonitko、Arkady G. Makarov、Samat B. Zikirin、Irina Yu. Bagryanskaya、Victor A. Bagryansky、Yuri V. Gatilov、Irina G. Irtegova、Makhmut M. Shakirov、Andrey V. Zibarev

  DOI：10.1021/ic102565x

  日期：2011.4.4

  Interaction between Ph3P and 1,3,2,4-benzodithiadiazine (I); its 6,7-difluoro (2), 5,6,8-trifluoro (3) and 5,6,7,8-tetrafluoro (4) derivatives; and 5,6,8-trifluoro-3,1,2,4-benzothiaselenadiazine (5) proceeded via a 1:1 condensation to give Ph3P=N-R iminophosphoranes (1a-5a, R = corresponding 1,2,3-benzodichalcogenazol-2-yls), which are inaccessible by general approaches based on the Staudinger and Kirsanov reactions. In contrast, neither Ph3As nor Ph3Sb reacted with 1 and 4. Molecular structures of 1a-5a and 5 were confirmed by X-ray diffraction (XRD). The crystals formed by chiral molecules of 2a-5a were racemic, whereas the crystal of la was formed by a single enantiomer. In all Of the Ph3P=N-R derivatives, one of the Ph rings is oriented face-to-face to the hetero ring, R. Upon heating to similar to 120 degrees C in squalane (1a, 3a, 4a) or dissolving in chloroform at ambient temperatures (1a, 2a, 4a) the Ph3P=N-R derivatives generated the 1,2,3-benzodithiazolyls (1b-4b, respectively) whose identity was confirmed by electron paramagnetic resonance (EPR). 2,1,3-Benzothiaselenazolyls 5b and 6b were detected by EPR as the main paramagnetic products of solution thermolysis of 5 and its 5,6,7,8-tetrafluoro congener (6), respectively. Passing a chloroform solution of 4a through silica column unexpectedly gave 5-6-6-6 tetracyclic (9) and 6-10-6 tricyclic (10) sulfur-nitrogen compounds, which were 'characterized by XRD.