2,4-dibromo-6[(2-diethylaminoethylimino)methyl]phenol | 1172613-61-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2,4-dibromo-6[(2-diethylaminoethylimino)methyl]phenol
• 英文别名: 2,4-Dibromo-6-[(2-diethylaminoethylimino)methyl]phenol；2,4-dibromo-6-[2-(diethylamino)ethyliminomethyl]phenol
• CAS: 1172613-61-4
• 化学式: C₁₃H₁₈Br₂N₂O
• 分子量: 378.107
• InChiKey: NUPDFZVOTSVHPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  35.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  copper(ll) bromide 、 2,4-dibromo-6[(2-diethylaminoethylimino)methyl]phenol 以 甲醇 为溶剂， 以81%的产率得到[copper(II)(bromide)(2,4-dibromo-6-[(2-diethylaminoethylimino)methyl]phenol(-H))]
  参考文献：
  名称：

  Syntheses and Crystal Structures of Two Schiff Base Copper(II) Complexes with Urease Inhibitory Activity

  摘要：

  Two new copper(II) complexes, [CuBrL1] (1) and [CuBrL2] (2) (HL1 = 1-[(2-diethylaminoethylimino)methyl] naphthalen-2ol, HL2 = 2,4-dibromo-6-[(2-diethylaminoethy limino) methyl]phenol), were prepared and structurally characterized by elemental analyses, infrared spectroscopy, and single-crystal X-ray diffraction. Both complexes are mononuclear copper(II) compounds. The Cu atom in each of the complexes is four-coordinate in a square planar geometry. Both complexes show potent urease inhibitory activities.

  DOI：

  10.1080/15533170902762603