| 1021690-29-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• CAS: 1021690-29-8
• 化学式: C₂₅H₃₉NO₂Sn
• 分子量: 504.3
• InChiKey: BQSXVUGLHONUMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.54
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  、 对硝基苯甲醛 在 四氯化锡 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 生成 2-[(2R,5S)-5-hydroxy-3-methylidene-5-(4-nitrophenyl)pentan-2-yl]isoindole-1,3-dione 、
  参考文献：
  名称：

  Binary 1,4-asymmetric induction from a single allyltin reagent with a chiral nitrogen functional group toward aldehydes

  摘要：

  Using a single allyltin reagent with a chiral nitrogen functionality, binary and remote asymmetric induction was realized toward various aldehydes. Either syn- or anti-1,4-amino-alcohols were selectively obtained with the use of Yb(OTf)(3) or SnCl4, respectively. The structures of both diastereomers were identified by means of X-ray analysis. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.01.112

文献信息

• Binary 1,4-asymmetric induction from a single allyltin reagent with a chiral nitrogen functional group toward aldehydes
  作者：Yutaka Nishigaichi、Ken-ichi Tamura、Narifumi Ueda、Hidetoshi Iwamoto、Akio Takuwa

  DOI：10.1016/j.tetlet.2008.01.112

  日期：2008.3

  Using a single allyltin reagent with a chiral nitrogen functionality, binary and remote asymmetric induction was realized toward various aldehydes. Either syn- or anti-1,4-amino-alcohols were selectively obtained with the use of Yb(OTf)(3) or SnCl4, respectively. The structures of both diastereomers were identified by means of X-ray analysis. (C) 2008 Elsevier Ltd. All rights reserved.