dibenzo[24]-crown-8 | 864666-13-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dibenzo[24]-crown-8
• 英文别名: 2,5,8,11,18,21,24,27-Octaoxatricyclo[26.4.0.012,17]dotriaconta-1(32),12(17),13,15,28,30-hexaen-14-ylmethyl 3,5-bis(but-3-enoxy)benzoate；2,5,8,11,18,21,24,27-octaoxatricyclo[26.4.0.012,17]dotriaconta-1(32),12(17),13,15,28,30-hexaen-14-ylmethyl 3,5-bis(but-3-enoxy)benzoate
• CAS: 864666-13-7
• 化学式: C₄₀H₅₀O₁₂
• 分子量: 722.83
• InChiKey: GHHNPSUEIMNSCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  52
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  119
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  dibenzo[24]-crown-8 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 、 [1,4-C₆H₄(CH₂NH₂C₇H₇)2][B(3,5-(CF₃)2C₆H₃)4]2 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以72%的产率得到
  参考文献：
  名称：

  Template-Directed Olefin Cross Metathesis

  摘要：

  A template containing two secondary dialkylammonium ion recognition sites for encirclement by olefin-bearing dibenzo[24]crown-8 derivatives has been used to promote olefin cross metatheses with ruthenium-alkylidene catalysts. For monoolefin monomers, the rates of metatheses and yields of the dimers are both amplified in the presence of the template. Likewise, for a diolefin monomer, the yield of the dimer is enhanced in the presence of the template under conditions where higher oligomers are not formed.

  DOI：

  10.1021/ol051599g
• 作为产物：
  描述：

  4-hydroxymethyldibenzo-24-crown-8 ether 、 3,5-bis(but-3-en-1-yloxy)benzoic acid 在 4-二甲氨基吡啶 、 1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 生成 dibenzo[24]-crown-8
  参考文献：
  名称：

  Template-Directed Olefin Cross Metathesis

  摘要：

  A template containing two secondary dialkylammonium ion recognition sites for encirclement by olefin-bearing dibenzo[24]crown-8 derivatives has been used to promote olefin cross metatheses with ruthenium-alkylidene catalysts. For monoolefin monomers, the rates of metatheses and yields of the dimers are both amplified in the presence of the template. Likewise, for a diolefin monomer, the yield of the dimer is enhanced in the presence of the template under conditions where higher oligomers are not formed.

  DOI：

  10.1021/ol051599g

文献信息

• Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET
  作者：Hongyi Hou、Ken C.-F. Leung、Daniela Lanari、Alshakim Nelson、J. Fraser Stoddart、Robert H. Grubbs

  DOI：10.1021/ja065572j

  日期：2006.12.1

  A trifurcated template, containing three secondary dialkylammonium ion recognition sites for encirclement by a dibenzo [24]crown-8-containing acyclic diene, is used to promote acyclic diene metatheses (ADMET) catalyzed by ruthenium-alkylidene complexes, affording a cyclic trimer in 55% yield. Following this one-step, threefold ADMET reaction, the resulting cyclic trimer was isolated by preparative HPLC and characterized by NMR spectroscopy and mass spectrometry.
• Template-Directed Olefin Cross Metathesis
  作者：Stuart J. Cantrill、Robert H. Grubbs、Daniela Lanari、Ken C.-F. Leung、Alshakim Nelson、Katherine G. Poulin-Kerstien、Sebastian P. Smidt、J. Fraser Stoddart、David A. Tirrell

  DOI：10.1021/ol051599g

  日期：2005.9.1

  A template containing two secondary dialkylammonium ion recognition sites for encirclement by olefin-bearing dibenzo[24]crown-8 derivatives has been used to promote olefin cross metatheses with ruthenium-alkylidene catalysts. For monoolefin monomers, the rates of metatheses and yields of the dimers are both amplified in the presence of the template. Likewise, for a diolefin monomer, the yield of the dimer is enhanced in the presence of the template under conditions where higher oligomers are not formed.