p-Nitro-benzoyljodid | 6561-59-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-Nitro-benzoyljodid
• 英文别名: 4-Nitrobenzoyl iodide
• CAS: 6561-59-7
• 化学式: C₇H₄INO₃
• 分子量: 277.018
• InChiKey: VOTRYGPPYSQQNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  62.9
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor
  申请人：United States of America as represented by the Administrator of NASA

  公开号：US10626098B2

  公开（公告）日：2020-04-21

  Copoly(imide oxetane) materials are disclosed that can exhibit a low surface energy while possessing the mechanical, thermal, chemical and optical properties associated with polyimides. The copoly(imide oxetane)s are prepared using a minor amount of fluorinated oxetane-derived oligomer with sufficient fluorine-containing segments of the copoly(imide oxetane)s migrate to the exterior surface of the polymeric material to yield low surface energies. Thus the coatings and articles of manufacture made with the copoly(imide oxetane)s of this invention are characterized as having an anisotropic fluorine composition. The low surface energies can be achieved with very low content of fluorinated oxetane-derived oligomer. The copolymers of this invention can enhance the viability of polyimides for many applications and may be acceptable where homopolyimide materials have been unacceptable.

  本发明公开了共聚（亚胺氧杂环丁烷）材料，这种材料表面能较低，同时具有与聚酰亚胺相关的机械、热、化学和光学特性。共聚（酰亚胺氧杂环丁烷）材料的制备使用了少量氟化氧杂环丁烷衍生的低聚物，共聚（酰亚胺氧杂环丁烷）材料中足够的含氟段迁移到聚合物材料的外表面，从而产生低表面能。因此，使用本发明的共聚（亚胺氧杂环丁烷）制造的涂层和制品具有各向异性氟组成的特点。低表面能可以通过极低的含氟氧杂环丁烷衍生低聚物含量来实现。本发明的共聚物可以提高聚酰亚胺在许多应用中的可行性，在均聚酰亚胺材料无法接受的情况下，本发明的共聚物也是可以接受的。
• Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor
  申请人：United States of America as represented by the Administrator of NASA

  公开号：US11130742B2

  公开（公告）日：2021-09-28

  Copoly(imide oxetane) materials are disclosed that can exhibit a low surface energy while possessing the mechanical, thermal, chemical and optical properties associated with polyimides. The copoly(imide oxetane)s are prepared using a minor amount of fluorinated oxetane-derived oligomer with sufficient fluorine-containing segments of the copoly(imide oxetane)s migrate to the exterior surface of the polymeric material to yield low surface energies. Thus the coatings and articles of manufacture made with the copoly(imide oxetane)s of this invention are characterized as having an anisotropic fluorine composition. The low surface energies can be achieved with very low content of fluorinated oxetane-derived oligomer. The copolymers of this invention can enhance the viability of polyimides for many applications and may be acceptable where homopolyimide materials have been unacceptable.

  本发明公开了共聚（亚胺氧杂环丁烷）材料，这种材料表面能较低，同时具有与聚酰亚胺相关的机械、热、化学和光学特性。共聚（酰亚胺氧杂环丁烷）材料的制备使用了少量氟化氧杂环丁烷衍生的低聚物，共聚（酰亚胺氧杂环丁烷）材料中足够的含氟段迁移到聚合物材料的外表面，从而产生低表面能。因此，使用本发明的共聚（亚胺氧杂环丁烷）制造的涂层和制品具有各向异性氟组成的特点。低表面能可以通过极低的含氟氧杂环丁烷衍生低聚物含量来实现。本发明的共聚物可以提高聚酰亚胺在许多应用中的可行性，在均聚酰亚胺材料无法接受的情况下，本发明的共聚物也是可以接受的。
• [EN] POLY (ADP-RIBOSE) POLYMERASE INHIBITOR<br/>[FR] INHIBITEUR DE POLY(ADP-RIBOSE) POLYMÉRASES
  申请人：CHENGDU DI AO PHARMACEUTICAL GROUP CO LTD

  公开号：WO2013078771A1

  公开（公告）日：2013-06-06

  本发明公开了一种邻苯二甲酰肼（酞嗪酮）类化合物，以及包括该类化合物的药物组合物。它们作为DNA修复酶多聚（ADP-核酶）聚合酶的抑制剂，可有效治疗涉及PARP酶活性的疾病，包括癌症、神经变性疾病、炎症等。
• NOVEL AMIDE GROUP-CONTAINING SILOXANE AMINE COMPOUND
  申请人：Sunaga Tomoyasu

  公开号：US20100137547A1

  公开（公告）日：2010-06-03

  A novel amide group-containing siloxane amine compound, which is useful as a diamine component of a polybenzimidazole resin, a polybenzoxazole resin, and particularly a polyimide resin, which is derived from an amine monomer, has a chemical structure represented by the formula (1). In the formula (1), R 1 and R 2 each independently represent an optionally substituted alkylene group; p denotes an integer of 0 to 3; q denotes an integer of 0 to 3; m denotes an integer of 1 to 30; and n denotes an integer of 0 to 20; provided that p and q are not 0 at the same time.
• Novel cc-1065 Analogs and Their Conjugates
  申请人：Beusker Patrick Henry

  公开号：US20110207767A1

  公开（公告）日：2011-08-25

  This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.