furan-2-carboxylic acid (4-tert-butyl-2-{3-[4-(6-morpholin-4-ylmethyl-pyridin-3-yl)-naphthalen-1-yl]-ureido}-phenyl)-amide | 501365-51-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: furan-2-carboxylic acid (4-tert-butyl-2-{3-[4-(6-morpholin-4-ylmethyl-pyridin-3-yl)-naphthalen-1-yl]-ureido}-phenyl)-amide
• 英文别名: N-[4-tert-butyl-2-[[4-[6-(morpholin-4-ylmethyl)pyridin-3-yl]naphthalen-1-yl]carbamoylamino]phenyl]furan-2-carboxamide
• CAS: 501365-51-1
• 化学式: C₃₆H₃₇N₅O₄
• 分子量: 603.721
• InChiKey: RVAVFVOISHIQLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  45
• 可旋转键数：
  8
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  109
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors
  申请人：Meade J.M. Christopher

  公开号：US20050163726A1

  公开（公告）日：2005-07-28

  The present invention relates to novel pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors, processes for preparing them and their use in the treatment of respiratory diseases.