Synthesis, Characterization and Biological Activity of Dioxouranium(VI) Complexes of Acyldipyridoxal Hydrazones
摘要:
Four acyl dipyridoxal hydrozones ligands, H4PLn, have been prepared by condensing the ester of the diacids, hydrazine hydrate and pyridoxal hydrochloride in 1 : 2 : 2 molar ratio. The UO2VI complexes of these ligands have been synthesized and characterized by various analytical and spectroscopic methods including X-ray crystallography. The ligands and UO2VI complexes have been tested for cytotoxicity. The solid-state structure of [(UO2)(4)(PL1)(2)(H2O)(4)]. 12H(2)O has been found to be a cyclic tetramer and this may or may not represent the structure of the bulk sample. The structures of bulk 1-4 have been proposed to be polymeric.