S-[2-(thiophene-2-carbonylsulfanyl)-1-benzothiophen-3-yl] thiophene-2-carbothioate | 1350535-24-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: S-[2-(thiophene-2-carbonylsulfanyl)-1-benzothiophen-3-yl] thiophene-2-carbothioate
• CAS: 1350535-24-8
• 化学式: C₁₈H₁₀O₂S₅
• 分子量: 418.606
• InChiKey: PJMMOFOEYSIVLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  170
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-噻吩甲酰氯 、 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 以 乙醚 、 四氢呋喃 为溶剂， 反应 1.0h， 以89%的产率得到S-[2-(thiophene-2-carbonylsulfanyl)-1-benzothiophen-3-yl] thiophene-2-carbothioate
  参考文献：
  名称：

  Synthesis of benzothiophene derivatives from dilithio reagents, sulfur, and electrophiles via electrophilic cyclization

  摘要：

  Benzothiophene derivatives were synthesized in high yields from readily available o-(alkynyllithio)aryllithio compounds, sulfur, and 2 equiv of acid chlorides or other electrophiles. An acid chloride-induced electrophilic cyclization resulted in the formation of the thiophene ring. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.098

文献信息

• Synthesis of benzothiophene derivatives from dilithio reagents, sulfur, and electrophiles via electrophilic cyclization
  作者：Zitao Wang、Weizhi Geng、Hanliu Wang、Shaoguang Zhang、Wen-Xiong Zhang、Zhenfeng Xi

  DOI：10.1016/j.tetlet.2011.10.098

  日期：2011.12

  Benzothiophene derivatives were synthesized in high yields from readily available o-(alkynyllithio)aryllithio compounds, sulfur, and 2 equiv of acid chlorides or other electrophiles. An acid chloride-induced electrophilic cyclization resulted in the formation of the thiophene ring. (C) 2011 Elsevier Ltd. All rights reserved.