furfurylidene-2-phenylthiourea | 484651-76-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: furfurylidene-2-phenylthiourea
• 英文别名: 1-(furan-2-ylmethylidene)-3-phenylthiourea
• CAS: 484651-76-5
• 化学式: C₁₂H₁₀N₂OS
• 分子量: 230.29
• InChiKey: KGMQMROYBNEQOE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  69.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  cobalt(II) chloride hexahydrate 、 furfurylidene-2-phenylthiourea 以 甲醇 为溶剂， 以65%的产率得到
  参考文献：
  名称：

  SYNTHESIS, PHYSICO-CHEMICAL CHARACTERIZATION, AND ANTIBACTERIAL STUDIES OF SOME BIOACTIVE SCHIFF BASES AND THEIR METAL CHELATES

  摘要：

  Complexes of Co(II), Ni(II) and Cu(II) with the Schiff bases salicylidene-2-aminophenol (H(2)SAPh), furfurylidene-N-phenylthiourea (FNPTU) and salicylidene-N-phenylthiourea (HSNPTU) have been synthesized and their physico-chemical properties have been investigated with the help of microanalytical data, UV-Vis, IR, ESR spectroscopy, TGA, conductance and magnetic susceptibility measurements. Non-isothermal kinetic and ligand field parameters of some complexes have been calculated. The general formula of the salicylidene-2-aminophenol Co(II) and Ni(II) complexes is [ML(H2O)(3)].2H(2)O and for the Cu(II) complex it is [CuL(H2O)].H2O. The furfurylidene-N-phenylthiourea and salicylidene-N-phenylthiourea complexes are of the general formulae [ML2Cl2].2H(2)O and [ML2].2H(2)O. These complexes have also been screened for their antibacterial properties and a few of them have been tested against tubercular bacteria.

  DOI：

  10.1081/sim-120014864