[2-[2,6-Bis[bis(3,5-difluorophenyl)phosphanylmethyl]phenyl]-3-[bis(3,5-difluorophenyl)phosphanylmethyl]phenyl]methyl-bis(3,5-difluorophenyl)phosphane | 1229618-96-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-[2,6-Bis[bis(3,5-difluorophenyl)phosphanylmethyl]phenyl]-3-[bis(3,5-difluorophenyl)phosphanylmethyl]phenyl]methyl-bis(3,5-difluorophenyl)phosphane
• 英文别名: [2-[2,6-bis[bis(3,5-difluorophenyl)phosphanylmethyl]phenyl]-3-[bis(3,5-difluorophenyl)phosphanylmethyl]phenyl]methyl-bis(3,5-difluorophenyl)phosphane
• CAS: 1229618-96-5
• 化学式: C₆₄H₃₈F₁₆P₄
• 分子量: 1234.88
• InChiKey: YOMDCKQXFRSDPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.6
• 重原子数：
  84
• 可旋转键数：
  17
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  16

文献信息

• Methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in hydroformylation processes
  申请人：Dow Technology Investments LLC

  公开号：US11130725B2

  公开（公告）日：2021-09-28

  The present invention relates to methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in a hydroformylation process. In one aspect, a method comprises (a) contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a tetraphosphine having the structure described herein, and, optionally, (C) a monophosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions; and (b) adding additional monophosphine having the structure described herein to a reaction zone.

  本发明涉及在加氢甲酰化过程中减缓催化剂失活和/或减缓四膦配体使用的方法。在一个方面，方法包括 (a) 使烯烃与一氧化碳、氢气和催化剂接触，催化剂包括 (A) 过渡金属，(B) 具有本文所述结构的四膦，以及可选地，(C) 具有本文所述结构的一膦，接触在一个或多个反应区和加氢甲酰化条件下进行；以及 (b) 向反应区添加额外的具有本文所述结构的一膦。
• Methods of controlling hydroformylation processes
  申请人：Dow Technology Investments LLC

  公开号：US11344869B2

  公开（公告）日：2022-05-31

  The present invention relates to methods of controlling hydroformylation processes for producing normal (N) and iso (I) aldehydes at a N:I ratio. In one aspect, a method of controlling a hydroformylation process comprises contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a monophosphine, and (C) a tetraphosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions to produce a blend of normal (N) and iso (I) aldehydes at a N:I ratio, the method comprising at least one of increasing the N:I ratio by adding additional tetraphosphine to a reaction zone; decreasing the N:I ratio by adding additional monophosphine to a reaction zone; or increasing the N:I ratio by volatilization of the free monophosphine.

  本发明涉及控制以 N:I 比例生产正（N）醛和异（I）醛的加氢甲酰化过程的方法。在一个方面，控制加氢甲酰化过程的方法包括将烯烃与一氧化碳、氢气和催化剂接触，催化剂包括(A)过渡金属、(B)一膦和(C)具有本文所述结构的四膦，接触在一个或多个反应区中并在加氢甲酰化条件下进行，以产生N:I比的正(N)醛和异(I)醛混合物：该方法包括通过向反应区添加额外的四膦来提高 N:I 比率；通过向反应区添加额外的一膦来降低 N:I 比率；或通过游离一膦的挥发来提高 N:I 比率中的至少一种。
• CATALYST COMPOSITIONS AND HYDROFORMYLATION PROCESSES
  申请人：Dow Technology Investments LLC

  公开号：US20210114010A1

  公开（公告）日：2021-04-22

  The present invention relates to catalyst compositions for hydroformylation processes and to hydroformylation processes utilizing certain catalysts. In one aspect, a catalyst composition for a hydroformylation process comprises (a) a transition metal; (b) a monophosphine; and (c) a tetraphosphine having the structure described herein, and wherein the composition comprises at least 40 moles of monophosphine per mole of transition metal.
• METHODS FOR SLOWING DEACTIVATION OF A CATALYST AND/OR SLOWING TETRAPHOSPHINE LIGAND USAGE IN HYDROFORMYLATION PROCESSES
  申请人：Dow Technology Investments LLC

  公开号：US20210114961A1

  公开（公告）日：2021-04-22

  The present invention relates to methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in a hydroformylation process. In one aspect, a method comprises (a) contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a tetraphosphine having the structure described herein, and, optionally, (C) a monophosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions; and (b) adding additional monophosphine having the structure described herein to a reaction zone.
• METHODS OF CONTROLLING HYDROFORMYLATION PROCESSES
  申请人：Dow Technology Investments LLC

  公开号：US20210362141A1

  公开（公告）日：2021-11-25

  The present invention relates to methods of controlling hydroformylation processes for producing normal (N) and iso (I) aldehydes at a N:I ratio. In one aspect, a method of controlling a hydroformylation process comprises contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a monophosphine, and (C) a tetraphosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions to produce a blend of normal (N) and iso (I) aldehydes at a N:I ratio, the method comprising at least one of increasing the N:I ratio by adding additional tetraphosphine to a reaction zone; decreasing the N:I ratio by adding additional monophosphine to a reaction zone; or increasing the N:I ratio by volatilization of the free monophosphine.