[2-[2,6-Bis[bis(4-methylphenyl)phosphanylmethyl]phenyl]-3-[bis(4-methylphenyl)phosphanylmethyl]phenyl]methyl-bis(4-methylphenyl)phosphane | 1229618-98-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-[2,6-Bis[bis(4-methylphenyl)phosphanylmethyl]phenyl]-3-[bis(4-methylphenyl)phosphanylmethyl]phenyl]methyl-bis(4-methylphenyl)phosphane
• 英文别名: [2-[2,6-bis[bis(4-methylphenyl)phosphanylmethyl]phenyl]-3-[bis(4-methylphenyl)phosphanylmethyl]phenyl]methyl-bis(4-methylphenyl)phosphane
• CAS: 1229618-98-7
• 化学式: C₇₂H₇₀P₄
• 分子量: 1059.24
• InChiKey: LOTUREMQHWOJPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  17
• 重原子数：
  76
• 可旋转键数：
  17
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2,2',6,6'-tetrakis((boraneyldi-p-tolyl-l5-phosphaneyl)methyl)-1,1'-biphenyl 在 三乙烯二胺 作用下， 以 甲苯 为溶剂， 以78%的产率得到[2-[2,6-Bis[bis(4-methylphenyl)phosphanylmethyl]phenyl]-3-[bis(4-methylphenyl)phosphanylmethyl]phenyl]methyl-bis(4-methylphenyl)phosphane
  参考文献：
  名称：

  四膦烷配体的合成及其在铑催化末端烯烃加氢甲酰化中的应用：高温下的高区域选择性

  摘要：

  已经开发出一类新型的取代四膦配体，并将其应用于铑催化的末端烯烃的区域选择性加氢甲酰化反应。考虑到在使用其他双膦类似物的类似反应条件下通常观察到的低区域选择性，这些四膦配体在高温（140°C）下显示出较高的区域选择性（1-辛烯和1-己烯的线性选择性高于97％）。 。还研究了二芳基膦部分上取代基的空间和电子效应。

  DOI：

  10.1002/chem.200903109

文献信息

• Methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in hydroformylation processes
  申请人：Dow Technology Investments LLC

  公开号：US11130725B2

  公开（公告）日：2021-09-28

  The present invention relates to methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in a hydroformylation process. In one aspect, a method comprises (a) contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a tetraphosphine having the structure described herein, and, optionally, (C) a monophosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions; and (b) adding additional monophosphine having the structure described herein to a reaction zone.

  本发明涉及在加氢甲酰化过程中减缓催化剂失活和/或减缓四膦配体使用的方法。在一个方面，方法包括 (a) 使烯烃与一氧化碳、氢气和催化剂接触，催化剂包括 (A) 过渡金属，(B) 具有本文所述结构的四膦，以及可选地，(C) 具有本文所述结构的一膦，接触在一个或多个反应区和加氢甲酰化条件下进行；以及 (b) 向反应区添加额外的具有本文所述结构的一膦。
• Methods of controlling hydroformylation processes
  申请人：Dow Technology Investments LLC

  公开号：US11344869B2

  公开（公告）日：2022-05-31

  The present invention relates to methods of controlling hydroformylation processes for producing normal (N) and iso (I) aldehydes at a N:I ratio. In one aspect, a method of controlling a hydroformylation process comprises contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a monophosphine, and (C) a tetraphosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions to produce a blend of normal (N) and iso (I) aldehydes at a N:I ratio, the method comprising at least one of increasing the N:I ratio by adding additional tetraphosphine to a reaction zone; decreasing the N:I ratio by adding additional monophosphine to a reaction zone; or increasing the N:I ratio by volatilization of the free monophosphine.

  本发明涉及控制以 N:I 比例生产正（N）醛和异（I）醛的加氢甲酰化过程的方法。在一个方面，控制加氢甲酰化过程的方法包括将烯烃与一氧化碳、氢气和催化剂接触，催化剂包括(A)过渡金属、(B)一膦和(C)具有本文所述结构的四膦，接触在一个或多个反应区中并在加氢甲酰化条件下进行，以产生N:I比的正(N)醛和异(I)醛混合物：该方法包括通过向反应区添加额外的四膦来提高 N:I 比率；通过向反应区添加额外的一膦来降低 N:I 比率；或通过游离一膦的挥发来提高 N:I 比率中的至少一种。
• CATALYST COMPOSITIONS AND HYDROFORMYLATION PROCESSES
  申请人：Dow Technology Investments LLC

  公开号：US20210114010A1

  公开（公告）日：2021-04-22

  The present invention relates to catalyst compositions for hydroformylation processes and to hydroformylation processes utilizing certain catalysts. In one aspect, a catalyst composition for a hydroformylation process comprises (a) a transition metal; (b) a monophosphine; and (c) a tetraphosphine having the structure described herein, and wherein the composition comprises at least 40 moles of monophosphine per mole of transition metal.
• METHODS FOR SLOWING DEACTIVATION OF A CATALYST AND/OR SLOWING TETRAPHOSPHINE LIGAND USAGE IN HYDROFORMYLATION PROCESSES
  申请人：Dow Technology Investments LLC

  公开号：US20210114961A1

  公开（公告）日：2021-04-22

  The present invention relates to methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in a hydroformylation process. In one aspect, a method comprises (a) contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a tetraphosphine having the structure described herein, and, optionally, (C) a monophosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions; and (b) adding additional monophosphine having the structure described herein to a reaction zone.
• METHODS OF CONTROLLING HYDROFORMYLATION PROCESSES
  申请人：Dow Technology Investments LLC

  公开号：US20210362141A1

  公开（公告）日：2021-11-25

  The present invention relates to methods of controlling hydroformylation processes for producing normal (N) and iso (I) aldehydes at a N:I ratio. In one aspect, a method of controlling a hydroformylation process comprises contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a monophosphine, and (C) a tetraphosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions to produce a blend of normal (N) and iso (I) aldehydes at a N:I ratio, the method comprising at least one of increasing the N:I ratio by adding additional tetraphosphine to a reaction zone; decreasing the N:I ratio by adding additional monophosphine to a reaction zone; or increasing the N:I ratio by volatilization of the free monophosphine.