1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Heptadecafluorononadecane | 931415-53-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Heptadecafluorononadecane
• CAS: 931415-53-1
• 化学式: C₁₉H₂₃F₁₇
• 分子量: 574.364
• InChiKey: VIPKARMAJZVVDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.6
• 重原子数：
  36
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  17

反应信息

• 作为产物：
  描述：

  全氟辛基碘烷 、 1-十一烯 生成 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Heptadecafluorononadecane
  参考文献：
  名称：

  Branching of the Perfluorinated Chain Influences the Liquid-Crystalline Properties of Semifluorinated Alkanes: Perfluorooctyl- and Perfluoroisononyl-n-Alkanes—a Comparative Study

  摘要：

  Two series of semifluorinated-n-alkanes (SFAs) of comparable perfluorinated chain length but, different terminal group constitution, namely perfluoroctyl-n-alkanes [F-(CF2)(8)-(CH2)(n)-H, in, short F8Hn] and perfluoroisononyl-n-alkanes [(CF3)(2)CF(CF2)(6)-(CH2)(n)-H, in short iF9Hn] were synthesized. Their thermal properties were analyzed by means of differential scanning calorimetry (DSC), on both heating and cooling of the samples. The textures of the synthesized semi-fluorinated alkanes were investigated with the microscopy in polarized light. Similar to previously investigated perfluorodecyl-n-alkanes, perfluorooctyl-n-alkanes containing fewer than 12 methylene groups form smectic B phase. F8H8, F8H9, and F8H10 show a tendency to supercool and preserve smectic B ordering even below the transition temperature. For F8H11, the phase transition front smectic B to 3D crystal structure, manifesting itself as a rapid recrystallization., has been. observed. Perfluorooetyl-n-alkanes of 12 or more methylene groups do not form liquid-crystalline phases. In contrast to perfluorooctyl-n-alkanes, perfluoroisononyl-n-alkanes are not capable of liquid-crystalline phase formation, regardless of the hydrogenated moiety length and the experimental conditions.

  DOI：

  10.1080/15421400600700430

文献信息

• [EN] METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS<br/>[FR] PROCÉDÉS ET COMPOSÉS POUR L'IDENTIFICATION D'INHIBITEURS DE GLYCOSYLTRANSFÉRASE
  申请人：HARVARD COLLEGE

  公开号：WO2013151697A1

  公开（公告）日：2013-10-10

  The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using compounds of Formula (I).

  本发明提供了用于筛选细菌糖基转移酶抑制剂的以莫诺霉素为基础的探针化合物的公式(I)。本发明还提供了使用公式(I)化合物进行细菌糖基转移酶筛选的检测方法。
• [EN] CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS<br/>[FR] PROCÉDÉS CHIMIO-ENZYMATIQUES POUR SYNTHÉTISER DES ANALOGUES DE LA MOÉNOMYCINE
  申请人：HARVARD COLLEGE

  公开号：WO2013152279A1

  公开（公告）日：2013-10-10

  The present invention provides methods of synthesizing moenomycin analogs of Formula (I). The present invention also provides compositions comprising a compound of Formula (I) and kits for synthesizing compounds of Formula (I).

  本发明提供了合成式(I)的莫诺霉素类似物的方法。本发明还提供了包含式(I)化合物的组合物和用于合成式(I)化合物的试剂盒。
• [EN] FLUORINATED PHOSPHONIC ACIDS<br/>[FR] ACIDES PHOSPHONIQUES FLUORES
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2003102003A1

  公开（公告）日：2003-12-11

  Fluorinated phosphonic acid compounds, useful as treatments for substrate surfaces, have the formula (I) : wherein: R1 is a straight chain alkylene group having from 3 to 21 carbon atoms, an oxa-substituted straight chain alkylene group having from 2 to 20 carbon atoms, or a thia-substituted straight chain alkylene group having from 2 to 20 carbon atoms; R2 is a perfluoroalkyl group having from 4 to 10 carbon atoms; R3 is hydrogen, an alkali metal cation, or an alkyl group having from 1 to 6 carbon atoms; and M is hydrogen or an alkali metal cation, with the proviso that if R1 is an unsubstituted straight chain alkylene group, then the sum of carbon atoms in R1 and R2 combined is at least 10.

  氟磷酸化合物，用作处理基板表面的药物，其化学式为（I）：其中：R1为具有3至21个碳原子的直链烷基基团，具有2至20个碳原子的氧代取代直链烷基基团，或具有2至20个碳原子的硫代取代直链烷基基团；R2为具有4至10个碳原子的全氟烷基基团；R3为氢、碱金属阳离子，或具有1至6个碳原子的烷基基团；M为氢或碱金属阳离子，但如果R1为未取代的直链烷基基团，则R1和R2中碳原子的总和至少为10。
• FLUORINATED PHOSPHONIC ACIDS
  申请人：3M Innovative Properties Company

  公开号：EP1509536A1

  公开（公告）日：2005-03-02
• METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS
  申请人：President and Fellows of Harvard College

  公开号：US20150079618A1

  公开（公告）日：2015-03-19

  The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using compounds of Formula (I).