2-Phenyl-7,8-benzochinazolon-(4) | 21419-52-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2-Phenyl-7,8-benzochinazolon-(4)
• 英文别名: 2-phenyl-3H-benzo[h]quinazolin-4-one；2-Phenyl-3H-benzo[h]chinazolin-4-on；2-phenyl-3H-benzo[h]quinazolin-4-one
• CAS: 21419-52-3
• 化学式: C₁₈H₁₂N₂O
• 分子量: 272.306
• InChiKey: HJBSTOXXXCEZAJ-UHFFFAOYSA-N

物化性质

• 熔点：
  311-313 °C(Solv: nitromethane (75-52-5))
• 沸点：
  491.0±28.0 °C(Predicted)
• 密度：
  1.26±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-氨基-2-萘甲腈 在 乙醇 、 sodium hydrogensulfite 、 potassium hydroxide 作用下， 以 N,N-二甲基乙酰胺 为溶剂， 反应 15.0h， 生成 2-Phenyl-7,8-benzochinazolon-(4)
  参考文献：
  名称：

  유기발광 화합물 및 이를 포함하는 유기전계발광소자

  摘要：

  本发明涉及有机发光化合物，其特征在于其为以下化学式1所表示的化合物。根据本发明采用有机发光化合物的有机电子发光器件，相比于传统的光致发光宿主材料，具有更低的驱动电压，具有良好的功率效率，同时具有较高的发光效率和寿命。[化学式1]

  公开号：

  KR20210133908A

文献信息

• Fiber-Type Transitions and Satellite Cell Activation in Low-Frequency-Stimulated Muscles of Young and Aging Rats
  作者：C. T. Putman、K. R. Sultan、T. Wassmer、J. A. Bamford、D. Skorjanc、D. Pette

  DOI：10.1093/gerona/56.12.b510

  日期：2001.12.1

  We examined satellite cell content and the activity of satellite cell progeny in tibialis anterior muscles of young (15 weeks) and aging (101 weeks) Brown Norway (BN) rats. after they were exposed for 50 days to a standardized and highly reproducible regime of chronic low-frequency electrical stimulation. Chronic low-frequency electrical stimulation was successful in inducing fast-to-slow fiber-type transformation, characterized by a 2.3-fold increase in the proportion of IIA fibers and fourfold and sevenfold decreases in the proportion of IID/X and IIB fibers in both young and aging BN rats. These changes were accompanied by a twofold increase in the satellite cell content in both the young and aging groups: satellite cell content reached a level that was significantly higher in the young group (p < .04). The total muscle precursor cell content (i.e., satellite cells plus progeny), however, did not differ between groups, because there was a greater number of satellite cell progeny passing through the proliferative and differentiative compartments of the aging group. The resulting 1.5-fold increase in myonuclear content was similar in the young and aging groups. We conclude that satellite cells and satellite cell progeny of aging BN rats possess an unaltered capacity to contribute to the adaptive response.
• ROBEV S. K., DOKL. BOLG. AN, 39,(1986) N 4, 47-50
  作者：ROBEV S. K.

  DOI：——

  日期：——