(5-Decyl-4,5-dihydro-1,2-oxazol-3-yl)-phenylmethanone | 1350536-66-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (5-Decyl-4,5-dihydro-1,2-oxazol-3-yl)-phenylmethanone
• 英文别名: (5-decyl-4,5-dihydro-1,2-oxazol-3-yl)-phenylmethanone
• CAS: 1350536-66-1
• 化学式: C₂₀H₂₉NO₂
• 分子量: 315.456
• InChiKey: RZYJAXFTBJKQNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  23
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-十二烯十二碳烯α-十二碳烯α-十二碳烯 、 苯甲酰硝基甲烷 在 silica gel-supported polyphosphoric acid 作用下， 以 甲苯 为溶剂， 反应 4.0h， 以99%的产率得到(5-Decyl-4,5-dihydro-1,2-oxazol-3-yl)-phenylmethanone
  参考文献：
  名称：

  Application of silica gel-supported polyphosphoric acid (PPA/SiO2) as a reusable solid acid catalyst to the synthesis of 3-benzoylisoxazoles and isoxazolines

  摘要：

  3-Benzoylisoxazoles were synthesized by the reaction of alkynes and benzoylnitromethane using silica gel-supported polyphosphoric acid (PPA/SiO2). This reaction provides a convenient, efficient, and reusable synthetic method of isoxazole derivatives. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.038

文献信息

• Application of silica gel-supported polyphosphoric acid (PPA/SiO2) as a reusable solid acid catalyst to the synthesis of 3-benzoylisoxazoles and isoxazolines
  作者：Ken-ichi Itoh、Tadashi Aoyama、Hiroaki Satoh、Yuki Fujii、Hiroshi Sakamaki、Toshio Takido、Mitsuo Kodomari

  DOI：10.1016/j.tetlet.2011.10.038

  日期：2011.12

  3-Benzoylisoxazoles were synthesized by the reaction of alkynes and benzoylnitromethane using silica gel-supported polyphosphoric acid (PPA/SiO2). This reaction provides a convenient, efficient, and reusable synthetic method of isoxazole derivatives. (C) 2011 Elsevier Ltd. All rights reserved.