10,22-Dihydro-4,5-dioxo-4,5-secopyropheophorbide-a | 138530-73-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 10,22-Dihydro-4,5-dioxo-4,5-secopyropheophorbide-a
• 英文别名: 3-[(2Z,3S,4S)-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-2-[2-[(3-ethyl-5-formyl-4-methyl-1H-pyrrol-2-yl)methyl]-3-methyl-4-oxo-1H-cyclopenta[b]pyrrol-6-ylidene]-4-methyl-3,4-dihydropyrrol-3-yl]propanoic acid
• CAS: 138530-73-1
• 化学式: C₃₃H₃₆N₄O₅
• 分子量: 568.673
• InChiKey: WUZYVYQUYUCJNR-LGSPFWPJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  42
• 可旋转键数：
  9
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  145
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  10,22-Dihydro-4,5-dioxo-4,5-secopyropheophorbide-a Methyl Ester 在 氢氧化钾 作用下， 以 甲醇 、 水 为溶剂， 反应 5.0h， 以86%的产率得到10,22-Dihydro-4,5-dioxo-4,5-secopyropheophorbide-a
  参考文献：
  名称：

  A biomimetic partial synthesis of the red chlorophyll-a catabolite from Chlorella protothecoides.

  摘要：

  The red bilin derivative which is excreted in the culture medium by Chlorella protothecoides when this microalgae is grown in a medium rich in glucose but poor in nitrogen has been synthesized in two steps from one of the products of photo-oxidation of the Cd(II) complex of pyropheophorbide-a methyl ester. Under the same conditions, the Zn(II) complex of the latter is transformed into a blue bilin derivative which is an isomer of the foregoing chlorophyll-a catabolite.

  DOI：

  10.1016/s0040-4020(01)89871-9